DR info

Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209

Crohn disease and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
96	Crohn disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
97	Ulcerative colitis
2	Amyotrophic lateral sclerosis
6	Parkinson disease
156	Rett syndrome
49	Systemic lupus erythematosus
70	Spinal stenosis
21	Mitochondrial disease
84	Sarcoidosis
8	Huntington disease
36	Epidermolysis bullosa
226	Interstitial cystitis with Hunners ulcer
298	Hereditary pancreatitis
113	Muscular dystrophy
65	Primary immunodeficiency
51	Scleroderma
50	Dermatomyositis
158	Tuberous sclerosis
22	Moyamoya disease
107	Juvenile idiopathic arthritis
11	Myasthenia gravis
17	Multiple system atrophy
206	Fragile X syndrome
53	Sjogren syndrome
19	Lysosomal storage disease
231	Alpha-1-antitrypsin deficiency
75	Cushing disease
98	Eosinophilic gastrointestinal disease
271	Ankylosing spondylitis
34	Neurofibromatosis
40	Takayasu arteritis
193	Prader-Willi syndrome
5	Progressive supranuclear palsy
78	Hypopituitarism
299	Cystic fibrosis
60	Aplastic anemia
85	Idiopathic interstitial pneumonia
41	Giant cell arteritis
205	Fragile X syndrome related disease
18	Spinocerebellar degeneration
162	Pemphigoid
93	Primary biliary cholangitis
95	Autoimmune hepatitis
140	Dorabe syndrome
144	Lennox-Gastaut syndrome
86	Pulmonary arterial hypertension
152	PCDH19 related syndrome
272	Fibrodysplasia ossificans progressiva
58	Hypertrophic cardiomyopathy
3	Spinal muscular atrophy
285	Fanconi anemia
56	Behcet disease
265	Lipodystrophy
296	Biliary atresia
63	Idiopathic thrombocytopenic purpura
283	Acquired pure red cell aplasia
45	Eosinophilic granulomatosis with Polyangiitis
145	West syndrome
66	IgA nephropathy
28	Systemic amyloidosis
284	Diamond-Blackfan anemia
222	Primary nephrotic syndrome
201	Angelman syndrome
35	Pemphigus
38	Stevens-Johnson syndrome
256	Muscle glycogenosis
44	Wegener granulomatosis
62	Paroxysmal nocturnal hemoglobinuria
164	Oculocutaneous albinism
42	Polyarteritis nodosa
55	Relapsing polychondritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
269	Pyogenic arthritis
224	Purpura nephritis
215	Tetralogy of Fallot
160	Congenital ichthyosis
155	Acquired aphasia with convulsive disorder
20	Adrenoleukodystrophy
168	Ehlers-Danlos syndrome
57	Idiopathic dilated cardiomyopathy
169	Menkes disease
170	Occipital horn syndrome
127	Frontotemporal lobar degeneration
167	Marfan syndrome
286	Hereditary sideroblastic anemia
94	Primary sclerosing cholangitis
326	Osteopetrosis
228	Bronchiolitis obliterans
280	Huge arteriovenous malformation with cervicofacial or limb lesion
43	Microscopic polyangiitis
61	Autoimmune hemolytic anemia
288	Autoimmune acquired coagulation factor deficiency
300	IgG4-related disease
236	Pseudohypoparathyroidism
118	Myelomeningocele
151	Rasmussen encephalitis
274	Osteogenesis Imperfecta
10	Charcot-Marie-Tooth disease
39	Toxic epidermal necrolysis
67	Polycystic kidney disease
227	Osler disease
90	Retinitis pigmentosa
64	Thrombotic thrombocytopenic purpura
25	Progressive multifocal leukoencephalopathy
157	Sturge-Weber syndrome
278	Huge lymphatic malformation with cervicofacial lesion
302	Leber hereditary optic neuropathy
294	Congenital diaphragmatic hernia
1	Spinal and bulbar muscular atrophy
26	HTLV-1-associated myelopathy
37	Generalised pustular psoriasis
81	Congenital adrenal hyperplasia
83	Addison disease
246	Methylmalonic acidemia
4	Primary lateral sclerosis
210	Single Ventricle
171	Wilson disease
310	Congenital anomalies syndrome
229	Autoimmune pulmonary alveolar proteinosis
323	Aromatic L-amino acid decarboxylase deficiency
270	Chronic recurrent multifocal osteomyelitis
218	Alport syndrome
76	Pituitary gonadotropin secretion hyperthyroidism
15	Inclusion body myositis
251	Urea cycle disorder
91	Budd-Chiari syndrome
71	Idiopathic osteonecrosis of the femoral head
212	Tricuspid atresia
88	Chronic thromboembolic pulmonary hypertension
268	Nakajo-Nishimura syndrome
325	Hereditary autoinflammatory syndrome
337	Homocystinuria
195	Noonan syndrome
263	Cerebrotendinous xanthomatosis
257	Hepatic glycogenosis
282	Congenital dyserythropoietic anemia
203	22q11.2 deletion syndrome
16	Crow-Fukase syndrome
211	Hypoplastic left heart syndrome
159	Xeroderma pigmentosum
331	Idiopathic multicentric castleman disease
89	Lymphangioleiomyomatosis
114	Non-dystrophic myotonia syndrome
14	Chronic inflammatory demyelinating polyneuropathy
225	Congenital nephrogenic diabetes insipidus
172	Hypophosphatasia
74	Prolactin secreting pituitary adenoma
179	Williams syndrome
333	Hutchinson-Gilford syndrome
238	Vitamin D-resistant rickets
235	Hypoparathyroidism
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
232	Carney complex
111	Congenital myopathy
99	Chronic intestinal pseudo-obstruction
191	Werner syndrome
52	Mixed connective tissue disease
220	Rapidly progressive glomerulonephritis
30	Distal myopathy