Aminolevulinic acid

4 diseases

ID	Disease name (Link within this page)	Number of trials
34	Neurofibromatosis	2
96	Crohn disease	1

ID	Disease name (Link within this page)	Number of trials
180	ATR-X syndrome	1
286	Hereditary sideroblastic anemia	2

34. Neurofibromatosis

Clinical trials : 133 / Drugs : 186 - (DrugBank : 67) / Drug target genes : 79 - Drug target pathways : 190

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02728388 (ClinicalTrials.gov)	August 2016	25/3/2016	Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II	Topical Photodynamic Therapy (PDT) With Levulan® Kerastick® for Benign Dermal Neurofibromas Phase II ...	NEUROFIBROMATOSIS 1	Drug: aminolevulinic acid	Harry T Whelan, MD	NULL	Recruiting	14 Years	30 Years	All	30	Phase 2	United States
2	NCT01682811 (ClinicalTrials.gov)	March 12, 2012	5/9/2012	Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)	Photodynamic Therapy for Benign Dermal Neurofibromas Using Levulan Kerastick For Topical Solution, P ...	Neurofibromatoses	Drug: Part 1 Levulan injection;Drug: Part 1 Levulan surface application;Drug: Part 1 Levulan surface ...	Harry T Whelan, MD	NULL	Completed	18 Years	90 Years	All	20	Phase 1	United States

Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04164849 (ClinicalTrials.gov)	November 22, 2019	8/11/2019	Extracorporeal Photopheresis of Patients With Crohn's Disease Using 5-aminolevulinic Acid	Extracorporeal Photopheresis of Patients With Crohn's Disease Using 5-aminolevulinic Acid	Crohn Disease	Drug: 5-aminolevulinic acid;Procedure: Blue light photopheresis;Procedure: Transfusion;Procedure: Co ...	University Hospital, Akershus	Oslo University Hospital	Recruiting	18 Years	N/A	All	10	Phase 1/Phase 2	Norway

Clinical trial : 1 / Drugs : 3 - (DrugBank : 2) / Drug target gene : 0 - Drug target pathway : 0

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCT2051220062	14/07/2022	14/07/2022	Physician-initiated clinical trial in patients with 5-aminolevulinic acid-induced ATR-X syndrome.	Exploratory study to investigate the safety and efficacy of NPJ005 in patients with ATR-X syndrome. ...	ATR-X syndrome infant, intellectual disability, epigenetics, guanine quadruplex;D008607	Containing 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) Tablets (25 mg ...	Wada Takahito	NULL	Recruiting	>= 2age old	Not applicable	Male	5	Phase 2	Japan

Clinical trials : 7 / Drugs : 20 - (DrugBank : 10) / Drug target genes : 8 - Drug target pathways : 43

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000023490	2016/08/20	05/08/2016	The Safety and Efficacy of 5-Aminolevulinic Acid (ALA) Therapy for Sideroblastic Anemia	The Safety and Efficacy of 5-Aminolevulinic Acid(ALA) Therapy for Sideroblastic Anemia - The Safety ...	Sideroblastic anemia (congenital and acquired)	Food supplement containing 150 mg of ALA phosphate was given per day for 24 weeks. For the evaluatio ...	Department of Hematolgy and Rheumatology, Tohoku University Graduate School of Medicine	NULL	Complete: follow-up complete	20years-old	80years-old	Male and Female	5	Not applicable	Japan
2	JPRN-UMIN000021407	2016/03/15	15/03/2016	A study of efficacy and safety of 5-aminolevulinic acidphosphate in patients with sideroblastic anem ...	A study of efficacy and safety of 5-aminolevulinic acidphosphate in patients with sideroblastic anem ...	sideroblastic anemia	Orally intake a 150 mg 5-aminolevulinic acid phosphate capsule once a day for up to 24 weeks.	Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University	SBI Pharmaceuticals Co., Ltd	Complete: follow-up continuing	20years-old	80years-old	Male and Female	5	Not applicable	Japan