LOSARTAN POTASSIUM

( DrugBank: Losartan, Potassium / KEGG DRUG: Losartan, Potassium )

5 diseases

ID	Disease name (Link within this page)	Number of trials
36	Epidermolysis bullosa	2
98	Eosinophilic gastrointestinal disease	2
167	Marfan syndrome	4

ID	Disease name (Link within this page)	Number of trials
179	Williams syndrome	1
215	Tetralogy of Fallot	1

36. Epidermolysis bullosa

Clinical trials : 163 / Drugs : 185 - (DrugBank : 46) / Drug target genes : 50 - Drug target pathways : 125

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2015-003670-32-AT (EUCTR)	05/10/2017	07/08/2017	Phase I/II trial to establish safety, tolerability and efficacy of losartan in children with epiderm ...	A dual-center prospective phase I/II trial to establish safety, tolerability and to obtain first dat ...	Recessive dystrophic epidermolysis bullosa (RDEB) MedDRA version: 20.0;Level: PT;Classification code ...	Trade Name: Losartan HEXAL INN or Proposed INN: losartan potassium Other descriptive name: LOSARTAN PO ...	Medical Center - University of Freiburg	NULL	Not Recruiting			Female: yes Male: yes	30	Phase 2	Austria;Germany
2	EUCTR2015-003670-32-DE (EUCTR)		07/04/2016	Phase I/II trial to establish safety, tolerability and efficacy of losartan in children with epiderm ...	A dual-center prospective phase I/II trial to establish safety, tolerability and to obtain first dat ...	Recessive dystrophic epidermolysis bullosa (RDEB) MedDRA version: 20.0;Level: PT;Classification code ...	Trade Name: Losartan HEXAL INN or Proposed INN: losartan potassium Other descriptive name: LOSARTAN PO ...	Medical Center - University of Freiburg	NULL	Not Recruiting			Female: yes Male: yes	30	Phase 2	Austria;Germany

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98. Eosinophilic gastrointestinal disease

Clinical trials : 172 / Drugs : 149 - (DrugBank : 39) / Drug target genes : 38 - Drug target pathways : 135

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03029091 (ClinicalTrials.gov)	May 23, 2017	20/1/2017	An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE)	A Preliminary Open-Label Trial of Losartan Potassiumin Participants With Eosinophilic Esophagitis (E ...	Eosinophilic Esophagitis	Drug: Losartan Potassium	Children's Hospital Medical Center, Cincinnati	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);National Institute of Aller ...	Completed	5 Years	25 Years	All	15	Phase 2	United States
2	NCT01808196 (ClinicalTrials.gov)	October 10, 2013	30/1/2013	Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD	A Preliminary, Open-label Trial of Losartan Potassiumin Participants With Eosinophilic Esophagitis ( ...	Eosinophilic Esophagitis;Connective Tissue Disorders	Drug: Losartan Potassium	Children's Hospital Medical Center, Cincinnati	NULL	Completed	5 Years	21 Years	All	6	Phase 2	United States

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167. Marfan syndrome

Clinical trials : 21 / Drugs : 40 - (DrugBank : 11) / Drug target genes : 10 - Drug target pathways : 50

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2007-005862-10-BE (EUCTR)	29/05/2009	07/01/2009	Randomized, double-blind study for the evaluation of the effect of losartan versus placebo on aortic ...	Randomized, double-blind study for the evaluation of the effect of losartan versus placebo on aortic ...	Marfan syndrome MedDRA version: 9.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome	Trade Name: Cozaar Product Name: Losartan INN or Proposed INN: Losartan potassium Trade Name: Coozar Pro ...	University Hospital Ghent	NULL	Not Recruiting			Female: yes Male: yes			Belgium
2	EUCTR2007-001125-97-ES (EUCTR)	20/05/2008	03/12/2007	Eficacia y Seguridad de Losartán vs Atenolol en la prevención de la dilatación progresiva de la aort ...	Eficacia y Seguridad de Losartán vs Atenolol en la prevención de la dilatación progresiva de la aort ...	The aortic dilatation in Marfan syndrome with two different treatments: losartan vs atenolol MedDRA ...	Trade Name: cozaar 50 INN or Proposed INN: LOSARTAN POTASSIUM Trade Name: blokium 50 INN or Proposed IN ...	alberto forteza	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Spain
3	NCT00429364 (ClinicalTrials.gov)	January 2007	29/1/2007	Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Sy ...	Trial of Beta Blocker Therapy (Atenolol) Versus Angiotensin II Receptor Blocker Therapy (Losartan) i ...	Marfan Syndrome	Drug: Losartan Potassium;Drug: Atenolol	New England Research Institutes	National Heart, Lung, and Blood Institute (NHLBI);FDA Office of Orphan Products Development;National ...	Completed	6 Months	25 Years	All	608	Phase 3	United States;Belgium;Canada
4	EUCTR2006-003991-37-BE (EUCTR)	13/12/2006	06/12/2006	Trial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in i ...	Trial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in i ...	Marfan syndrome MedDRA version: 8.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome	Product Name: losartan INN or Proposed INN: Losartan potassium Product Name: losartan INN or Proposed I ...	University Hospital Gent	NULL	Not Recruiting			Female: yes Male: yes	600		Belgium

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179. Williams syndrome

Clinical trials : 5 / Drugs : 14 - (DrugBank : 7) / Drug target genes : 8 - Drug target pathways : 32

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2007-006059-37-ES (EUCTR)	27/05/2009	19/08/2008	ENSAYO CLÍNICO PILOTO, ALEATORIZADO, CONTROLADO, PARALELO, DOBLE-CIEGO, PARA EVALUAR LA EFICACIA Y S ...	ENSAYO CLÍNICO PILOTO, ALEATORIZADO, CONTROLADO, PARALELO, DOBLE-CIEGO, PARA EVALUAR LA EFICACIA Y S ...	Pacientes con síndrome de Williams con evidencia molecular de microdeleción en 7q11.2. Edad: Niños d ...	Trade Name: COZAAR 50 mg comprimidos recubierto con pelicula INN or Proposed INN: LOSARTAN POTASICO Ot ...	Programa de Medicina Molecular y Genética, Hospital Vall d´Hebron	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60		Spain

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215. Tetralogy of Fallot

Clinical trials : 18 / Drugs : 26 - (DrugBank : 14) / Drug target genes : 13 - Drug target pathways : 45

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2013-002091-41-NL (EUCTR)	09/10/2014	05/11/2013	Research into the effect of the drug losartan in adult patients with a reduced function of the right ...	Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosteron ...	To study the effect of losartan in adult patients with Tetralogy of Fallot and right ventricular dys ...	Trade Name: Losartan Product Name: Losartan INN or Proposed INN: Losartan Potassium Other descriptive n ...	Academisch medisch centrum	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Netherlands

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