Sitaxsentan and Sildenafil

( DrugBank: Sildenafil, Sitaxsentan / KEGG DRUG: Sildenafil, Sitaxentan )

1 disease

ID	Disease name (Link within this page)	Number of trials
86	Pulmonary arterial hypertension	3

86. Pulmonary arterial hypertension

Clinical trials : 1,205 / Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193

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Showing 1 to 3 of 3 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01244620 (ClinicalTrials.gov)	November 2010	15/11/2010	A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between ...	A Phase 1, Open Label, Randomized, Four Period, Crossover, Multiple Dose Study To Assess The Pharmac ...	Pulmonary Arterial Hypertension	Drug: sitaxentan;Drug: tadalafil;Drug: sitaxsentan;Drug: sildenafil	Pfizer	NULL	Terminated	21 Years	55 Years	All	16	Phase 1	Singapore
2	NCT00796510 (ClinicalTrials.gov)	July 2010	20/11/2008	Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjec ...	A Phase 3, Multi-Center, Open Label Study To Evaluate The Long-Term Safety Of Monotherapy Sitaxsenta ...	Pulmonary Arterial Hypertension;Pulmonary Hypertension	Drug: Sitaxsentan;Drug: Sitaxsentan and Sildenafil	Pfizer	NULL	Terminated	16 Years	80 Years	All	3	Phase 3	United States;Romania;Ukraine;Argentina;Bulgaria;Chile;China;Colombia;Costa Rica;Czech Republic;Domi ...
3	NCT00796666 (ClinicalTrials.gov)	May 2009	20/11/2008	Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR ...	A Phase 3, Multi-Center, Randomized, Double-Blind, Efficacy And Safety Study Of Monotherapy Sitaxsen ...	Pulmonary Arterial Hypertension;Pulmonary Hypertension	Drug: Sitaxsentan;Drug: Sitaxsentan and Sildenafil	Pfizer	NULL	Terminated	16 Years	80 Years	All	131	Phase 3	United States;Argentina;Bulgaria;Chile;China;Colombia;Czech Republic;India;Malaysia;Mexico;Peru;Roma ...

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