Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Amniotic epithelial cells	Amniotic Epithelial Cells	-	-	-	1件: 26 💬
2	Bortezomib	Bortezomib	1件: D03150 💬	1件: PSMB5 💬	8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
3	Ciclosporin	Cyclosporine	1件: D00184 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	32件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	13件: 26, 46, 49, 50, 53, 55, 60, 61, 97, 222, 226, 228, 269 💬
4	Costicosteroids	-	-	-	-	1件: 26 💬
5	Cyclophosphamide	Cyclophosphamide	2件: D00287, D07760 💬	-	-	44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
6	Doxorubicin	Doxorubicin	1件: D03899 💬	2件: TOP2A, TOP2B 💬	1件: Platinum drug resistance	4件: 26, 28, 34, 331 💬
7	Doxorubicin hydrochloride	Doxorubicin	1件: D03899 💬	2件: TOP2A, TOP2B 💬	1件: Platinum drug resistance	3件: 26, 34, 331 💬
8	Etoposide	Etoposide	2件: D00125, D04107 💬	2件: TOP2A, TOP2B 💬	1件: Platinum drug resistance	11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
9	Filgrastim	Filgrastim	1件: D03235 💬	1件: CSF3R 💬	5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	27件:  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
10	Hu mik-beta-1	-	-	-	-	1件: 26 💬
11	Human interferon beta	Human interferon beta	-	-	-	2件: 13, 26 💬
12	Interferon alfa	Interferon alfa	1件: D03305 💬	2件: IFNAR1, IFNAR2 💬	18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	5件: 25, 26, 28, 56, 96 💬
13	Interferon beta	Human interferon beta	-	-	-	5件: 13, 20, 26, 96, 97 💬
14	Interferon beta-1a	Human interferon beta	1件: D04554 💬	2件: IFNAR1, IFNAR2 💬	18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	4件: 13, 26, 96, 97 💬
15	Kw-0761	-	-	-	-	1件: 26 💬
16	Kw-0761 0.3 mg/kg iv	-	-	-	-	1件: 26 💬
17	Lamivudine	Lamivudine	1件: D00353 💬	-	-	6件: 26, 42, 46, 135, 265, 325 💬
18	Lenalidomide	Lenalidomide	1件: D04687 💬	1件: TNF 💬	65件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	7件: 16, 26, 28, 34, 49, 284, 300 💬
19	Methylprednisolone	Methylprednisolone	6件: D00407, D00751, D00979, D05000, D05001, D05002 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	44件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
20	Mogamulizumab	Mogamulizumab	1件: D09761 💬	1件: CCR4 💬	5件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Kaposi sarcoma-associated herpesvirus infection, Viral carcinogenesis, Viral protein interaction with cytokine and cytokine receptor	1件: 26 💬
21	Nivolumab	Nivolumab	1件: D10316 💬	1件: PDCD1 💬	3件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway	12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
22	Nk cells	Natural Killer Cell	-	-	-	1件: 26 💬
23	Other: laboratory biomarker analysis	-	-	-	-	21件: 11, 13, 14, 16, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 232, 283, 284, 285, 298, 331 💬
24	Other: pharmacogenomic study	-	-	-	-	1件: 26 💬
25	Pentosan polysulfate	Pentosan polysulfate	1件: D05428 💬	-	-	3件: 19, 26, 226 💬
26	Pentoxifylline	Pentoxifylline	1件: D00501 💬	-	-	10件: 26, 56, 84, 93, 96, 113, 220, 222, 296, 298 💬
27	Prednisolone	Prednisolone	8件: D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
28	Prednisone	Prednisone	1件: D00473 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	47件:  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
29	Propantheline	Propantheline	1件: D00481 💬	5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	1件: 26 💬
30	Propantheline bromide	Propantheline	1件: D00481 💬	5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	1件: 26 💬
31	Raltegravir	Raltegravir	1件: D06676 💬	-	-	4件: 13, 26, 93, 265 💬
32	Raltegravir and zidovudine	Raltegravir	2件: D00413, D06676 💬	-	-	1件: 26 💬
33	Recombinant human interferon beta-1a	Human interferon beta	1件: D04554 💬	2件: IFNAR1, IFNAR2 💬	18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	1件: 26 💬
34	Recombinant interferon alfa	Interferon alfa	1件: D03305 💬	2件: IFNAR1, IFNAR2 💬	18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	2件: 26, 28 💬
35	Sulfate	Sulfate ion	-	-	-	25件:  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
36	Tamibarotene	Tamibarotene	1件: D01418 💬	1件: RARA 💬	5件: Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer	2件: 26, 96 💬
37	Valproic acid	Valproic acid	1件: D00399 💬	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	10件:  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬
38	Valproid acid plus corticosteroids	-	-	-	-	1件: 26 💬
39	Vincristine	Vincristine	2件: D02197, D08679 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	3件: 26, 34, 331 💬
40	Vincristine sulfate	Sulfate ion	2件: D02197, D08679 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	2件: 26, 34 💬
41	Zidovudine	Zidovudine	1件: D00413 💬	-	-	6件: 25, 26, 135, 265, 325, 331 💬
42	Zidovudine/lamivudine	Lamivudine	2件: D00353, D00413 💬	-	-	1件: 26 💬

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