DDrare: Database of Drug Development for Rare Diseases

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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Extended-release oxycodone	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 13 💬
2	Oxycodone	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	7件: 6 , 13, 46, 70, 226, 231, 298 💬
3	Oxycodone by patient-controlled analgesia (pca)	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 46 💬
4	Oxycodone depot ”sandoz”, depot tablets	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 298 💬
5	Oxycodone hydrochloride	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	4件: 6 , 70, 226, 298 💬
6	Oxycodone naloxone prolonged release tablets	Naloxone	5件: D01340, D03783, D05312, D05462, D08249 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 226 💬
7	Oxycodone orion	Oxycodone	3件: D03783, D05312, D05462 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 70 💬
8	Oxycodone/acetaminophen	Acetaminophen	4件: D00217, D03783, D05312, D05462 💬	5件: OPRD1, OPRK1, OPRM1, PTGS1, PTGS2 💬	28件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Sphingolipid signaling pathway, TNF signaling pathway, VEGF signaling pathway, cGMP-PKG signaling pathway	1件: 231 💬
9	Oxycodone/naloxone prolonged release t	Naloxone	5件: D01340, D03783, D05312, D05462, D08249 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 226 💬
10	Oxycodone/naloxone prolonged release tablets	Naloxone	5件: D01340, D03783, D05312, D05462, D08249 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	1件: 6 💬

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