Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A 1件: SCN5A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A 1件: SCN5A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |
3 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
PGR 1件: PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 1件: 10 💬 |
4 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
5 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 1件: OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
6 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
7 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A 1件: SCN1A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |
8 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A 1件: SCN1A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |
9 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
10 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 1件: OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
11 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
12 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
PGR 1件: PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 1件: 10 💬 |
13 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
14 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
15 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
16 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 1件: OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
17 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
18 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
19 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
20 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
21 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PGR 1件: PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 1件: 10 💬 |
22 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PGR 1件: PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 1件: 10 💬 |
23 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 1件: OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
24 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
25 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 5件: 2 , 10, 13, 18, 149 💬 |
26 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A 3件: SCN2A, SCN3A, SCN9A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |
27 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A 3件: SCN2A, SCN3A, SCN9A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 5件: 1 , 2 , 10, 113, 114 💬 |