DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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90 / 286 pathways

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3	African trypanosomiasis 💬	1件: IFNG 💬	D11120 💬	Emapalumab	1件: 107 💬
4	African trypanosomiasis 💬	1件: IL1B 💬	D09315 💬	Canakinumab	10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
5	African trypanosomiasis 💬	1件: IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
6	AGE-RAGE signaling pathway in diabetic complications 💬	2件: IL1A, IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
7	AGE-RAGE signaling pathway in diabetic complications 💬	1件: IL1B 💬	D09315 💬	Canakinumab	10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
9	AGE-RAGE signaling pathway in diabetic complications 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
10	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬

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