DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: MTOR 💬	D02714 💬	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
2	Acute myeloid leukemia 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
3	Adipocytokine signaling pathway 💬	1件: MTOR 💬	D02714 💬	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
4	Adipocytokine signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
5	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
6	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
7	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
8	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
9	Alanine, aspartate and glutamate metabolism 💬	1件: ABAT 💬	D00535 💬	Vigabatrin	2件: 145, 158 💬
10	Alzheimer disease 💬	1件: MTOR 💬	D02714 💬	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬

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