Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
2	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
3	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00076 💬	Norepinephrine	1件: 22 💬
4	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D05206 💬	Norepinephrine	1件: 22 💬
5	Alzheimer disease 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
6	AMPK signaling pathway 💬	1件: ADRA1A 💬	D00076 💬	Norepinephrine	1件: 22 💬
7	AMPK signaling pathway 💬	1件: ADRA1A 💬	D05206 💬	Norepinephrine	1件: 22 💬
8	AMPK signaling pathway 💬	1件: ADRA1A 💬	D00511 💬	Phenylephrine	1件: 22 💬
9	AMPK signaling pathway 💬	1件: ADRA1A 💬	D08365 💬	Phenylephrine	1件: 22 💬
10	Arachidonic acid metabolism 💬	2件: PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
11	C-type lectin receptor signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
12	Calcium signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
13	Calcium signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
14	Calcium signaling pathway 💬	6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
15	Calcium signaling pathway 💬	6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
16	cAMP signaling pathway 💬	2件: ADRB1, ADRB2 💬	D00076 💬	Norepinephrine	1件: 22 💬
17	cAMP signaling pathway 💬	2件: ADRB1, ADRB2 💬	D05206 💬	Norepinephrine	1件: 22 💬
18	cGMP-PKG signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
19	cGMP-PKG signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
20	cGMP-PKG signaling pathway 💬	9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
21	cGMP-PKG signaling pathway 💬	9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
22	Chemical carcinogenesis 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
23	Cytokine-cytokine receptor interaction 💬	1件: EPOR 💬	D03231 💬	Erythropoietin	10件:  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
24	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D00076 💬	Norepinephrine	1件: 22 💬
25	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D05206 💬	Norepinephrine	1件: 22 💬
26	GABAergic synapse 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
27	Gap junction 💬	1件: ADRB1 💬	D00076 💬	Norepinephrine	1件: 22 💬
28	Gap junction 💬	1件: ADRB1 💬	D05206 💬	Norepinephrine	1件: 22 💬
29	Hematopoietic cell lineage 💬	1件: EPOR 💬	D03231 💬	Erythropoietin	10件:  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
30	Human cytomegalovirus infection 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
31	Human papillomavirus infection 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
32	IL-17 signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
33	JAK-STAT signaling pathway 💬	1件: EPOR 💬	D03231 💬	Erythropoietin	10件:  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
34	Kaposi sarcoma-associated herpesvirus infection 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
35	Leishmaniasis 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
36	Metabolic pathways 💬	2件: PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
37	MicroRNAs in cancer 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
38	Morphine addiction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
39	Neuroactive ligand-receptor interaction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
40	Neuroactive ligand-receptor interaction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
41	Neuroactive ligand-receptor interaction 💬	9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
42	Neuroactive ligand-receptor interaction 💬	9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
43	Neuroactive ligand-receptor interaction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
44	NF-kappa B signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
45	Nicotine addiction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
46	Ovarian steroidogenesis 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
47	Oxytocin signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
48	Pathways in cancer 💬	1件: EPOR 💬	D03231 💬	Erythropoietin	10件:  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
49	Pathways in cancer 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
50	Pathways of neurodegeneration - multiple diseases 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
51	PI3K-Akt signaling pathway 💬	1件: EPOR 💬	D03231 💬	Erythropoietin	10件:  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
52	Platelet activation 💬	1件: PTGS1 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
53	Regulation of lipolysis in adipocytes 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
54	Regulation of lipolysis in adipocytes 💬	3件: ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
55	Regulation of lipolysis in adipocytes 💬	2件: PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
56	Renin secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
57	Renin secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
58	Retrograde endocannabinoid signaling 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
59	Retrograde endocannabinoid signaling 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
60	Salivary secretion 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
61	Salivary secretion 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
62	Salivary secretion 💬	6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
63	Salivary secretion 💬	6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
64	Serotonergic synapse 💬	3件: GABRB1, GABRB2, GABRB3 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
65	Serotonergic synapse 💬	2件: PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
66	Small cell lung cancer 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
67	Taste transduction 💬	6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00549 💬	Propofol	9件:  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
68	Thermogenesis 💬	1件: ADRB3 💬	D00076 💬	Norepinephrine	1件: 22 💬
69	Thermogenesis 💬	1件: ADRB3 💬	D05206 💬	Norepinephrine	1件: 22 💬
70	TNF signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
71	Vascular smooth muscle contraction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00076 💬	Norepinephrine	1件: 22 💬
72	Vascular smooth muscle contraction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D05206 💬	Norepinephrine	1件: 22 💬
73	Vascular smooth muscle contraction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00511 💬	Phenylephrine	1件: 22 💬
74	Vascular smooth muscle contraction 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08365 💬	Phenylephrine	1件: 22 💬
75	VEGF signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬

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