DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00400 💬	Valsartan	7件: 57, 58, 66, 75, 218, 222, 224 💬
2	Adrenergic signaling in cardiomyocytes 💬	2件: AGTR1, AGTR2 💬	D00150 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
3	Adrenergic signaling in cardiomyocytes 💬	2件: AGTR1, AGTR2 💬	D02014 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00150 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D02014 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
6	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00400 💬	Valsartan	7件: 57, 58, 66, 75, 218, 222, 224 💬
7	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D00150 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
8	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D02014 💬	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224 💬
9	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D00400 💬	Valsartan	7件: 57, 58, 66, 75, 218, 222, 224 💬
10	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬

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