DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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94 / 286 pathways

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adherens junction 💬	1件: IGF1R 💬	D03297 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
2	Adherens junction 💬	1件: IGF1R 💬	D04870 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
3	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
4	Adipocytokine signaling pathway 💬	1件: LEPR 💬	D05014 💬	Metreleptin	1件: 265 💬
5	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
6	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
7	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
9	Alcoholism 💬	1件: ADORA2A 💬	D00528 💬	Caffeine	9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
10	Alcoholism 💬	1件: ADORA2A 💬	D01453 💬	Caffeine	9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬

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