DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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74 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	AGE-RAGE signaling pathway in diabetic complications 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
2	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
3	Amoebiasis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
4	Amphetamine addiction 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
5	Amyotrophic lateral sclerosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
6	Axon guidance 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
7	B cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
8	Breast cancer 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
9	C-type lectin receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
10	Calcium signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
11	Cell cycle 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
12	Cellular senescence 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
13	Cellular senescence 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
14	cGMP-PKG signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15	Chagas disease 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
16	Chronic myeloid leukemia 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
17	Colorectal cancer 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
18	Cytokine-cytokine receptor interaction 💬	1件: GHR 💬	D02691 💬	Somatotropin	20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
19	Cytokine-cytokine receptor interaction 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
20	Cytokine-cytokine receptor interaction 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
21	Diabetic cardiomyopathy 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
22	Dilated cardiomyopathy 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
23	Dopaminergic synapse 💬	3件: PPP3CA, PPP3CB, PPP3CC 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
24	Endocrine and other factor-regulated calcium reabsorption 💬	1件: PTH1R 💬	D06078 💬	Teriparatide	7件: 46, 65, 68, 70, 71, 235, 274 💬
25	FoxO signaling pathway 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
26	Gastric cancer 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
27	Glucagon signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
28	Glutamatergic synapse 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
29	Growth hormone synthesis, secretion and action 💬	1件: GHR 💬	D02691 💬	Somatotropin	20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
30	Hematopoietic cell lineage 💬	1件: MS4A1 💬	D02994 💬	Rituximab	47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
31	Hepatitis B 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
32	Hepatocellular carcinoma 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
33	Hippo signaling pathway 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
34	Human cytomegalovirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
35	Human immunodeficiency virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
36	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D00939 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
37	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D07119 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
38	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D08056 💬	Ibandronate	3件: 46, 49, 274 💬
39	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D00941 💬	Pamidronic acid	2件: 271, 274 💬
40	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D07281 💬	Pamidronic acid	2件: 271, 274 💬
41	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
42	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
43	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
44	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
45	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
46	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
47	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
48	Human T-cell leukemia virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
49	Human T-cell leukemia virus 1 infection 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
50	Hypertrophic cardiomyopathy 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
51	Inflammatory bowel disease 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
52	Influenza A 💬	1件: FDPS 💬	D00939 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
53	Influenza A 💬	1件: FDPS 💬	D07119 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
54	Influenza A 💬	1件: FDPS 💬	D08056 💬	Ibandronate	3件: 46, 49, 274 💬
55	Influenza A 💬	1件: FDPS 💬	D00941 💬	Pamidronic acid	2件: 271, 274 💬
56	Influenza A 💬	1件: FDPS 💬	D07281 💬	Pamidronic acid	2件: 271, 274 💬
57	Influenza A 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
58	Influenza A 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
59	Influenza A 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
60	Influenza A 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
61	Influenza A 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
62	Influenza A 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
63	Influenza A 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
64	Intestinal immune network for IgA production 💬	1件: TGFB1 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
65	JAK-STAT signaling pathway 💬	1件: GHR 💬	D02691 💬	Somatotropin	20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
66	Kaposi sarcoma-associated herpesvirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
67	Leishmaniasis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
68	Long-term potentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
69	Malaria 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
70	MAPK signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
71	MAPK signaling pathway 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
72	Metabolic pathways 💬	1件: FDPS 💬	D00939 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
73	Metabolic pathways 💬	1件: FDPS 💬	D07119 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
74	Metabolic pathways 💬	1件: FDPS 💬	D08056 💬	Ibandronate	3件: 46, 49, 274 💬
75	Metabolic pathways 💬	1件: FDPS 💬	D00941 💬	Pamidronic acid	2件: 271, 274 💬
76	Metabolic pathways 💬	1件: FDPS 💬	D07281 💬	Pamidronic acid	2件: 271, 274 💬
77	Metabolic pathways 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
78	Metabolic pathways 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
79	Metabolic pathways 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
80	Metabolic pathways 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
81	Metabolic pathways 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
82	Metabolic pathways 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
83	Metabolic pathways 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
84	MicroRNAs in cancer 💬	1件: TGFB2 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
85	Natural killer cell mediated cytotoxicity 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
86	Neuroactive ligand-receptor interaction 💬	1件: GHR 💬	D02691 💬	Somatotropin	20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
87	Neuroactive ligand-receptor interaction 💬	1件: PTH1R 💬	D06078 💬	Teriparatide	7件: 46, 65, 68, 70, 71, 235, 274 💬
88	NF-kappa B signaling pathway 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
89	Non-alcoholic fatty liver disease 💬	1件: TGFB1 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
90	Oocyte meiosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
91	Osteoclast differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
92	Osteoclast differentiation 💬	2件: TGFB1, TGFB2 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
93	Osteoclast differentiation 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
94	Oxytocin signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
95	Pancreatic cancer 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
96	Parathyroid hormone synthesis, secretion and action 💬	1件: PTH1R 💬	D06078 💬	Teriparatide	7件: 46, 65, 68, 70, 71, 235, 274 💬
97	Parathyroid hormone synthesis, secretion and action 💬	1件: SOST 💬	D10156 💬	Romosozumab	2件: 46, 274 💬
98	Parathyroid hormone synthesis, secretion and action 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
99	Pathways in cancer 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
100	Pathways of neurodegeneration - multiple diseases 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
101	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
102	PI3K-Akt signaling pathway 💬	1件: GHR 💬	D02691 💬	Somatotropin	20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
103	Prion disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
104	Prolactin signaling pathway 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
105	Proteoglycans in cancer 💬	2件: TGFB1, TGFB2 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
106	Relaxin signaling pathway 💬	1件: TGFB1 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
107	Renal cell carcinoma 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
108	Renin secretion 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
109	Rheumatoid arthritis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
110	Rheumatoid arthritis 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
111	T cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
112	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D00939 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
113	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D07119 💬	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299 💬
114	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D08056 💬	Ibandronate	3件: 46, 49, 274 💬
115	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D00941 💬	Pamidronic acid	2件: 271, 274 💬
116	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D07281 💬	Pamidronic acid	2件: 271, 274 💬
117	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
118	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
119	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
120	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
121	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
122	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
123	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
124	TGF-beta signaling pathway 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
125	Th1 and Th2 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
126	Th17 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
127	Th17 cell differentiation 💬	1件: TGFB1 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
128	Toxoplasmosis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
129	Tuberculosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
130	Tuberculosis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
131	VEGF signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
132	Wnt signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
133	Wnt signaling pathway 💬	1件: SOST 💬	D10156 💬	Romosozumab	2件: 46, 274 💬

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