DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
2	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
3	African trypanosomiasis 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
4	African trypanosomiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
6	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
7	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
8	Allograft rejection 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
9	Allograft rejection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10	Alzheimer disease 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬

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