DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
2	Acute myeloid leukemia 💬	1件: RARA 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
3	Adipocytokine signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
4	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
5	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
6	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬	D02716 💬	Pregabalin	5件: 13, 36, 46, 70, 298 💬
7	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D04048 💬	Ropivacaine	3件: 36, 46, 70 💬
8	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D08490 💬	Ropivacaine	3件: 36, 46, 70 💬
9	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

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