DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2	Acute myeloid leukemia 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3	AMPK signaling pathway 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
4	AMPK signaling pathway 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
5	Axon guidance 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6	Axon guidance 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
7	Bile secretion 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
8	Bile secretion 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
9	Biosynthesis of cofactors 💬	2件: NQO1, VKORC1 💬	D00564 💬	Warfarin	11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬
10	Biosynthesis of cofactors 💬	2件: NQO1, VKORC1 💬	D01280 💬	Warfarin	11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬

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