DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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107 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
3	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
4	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
5	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
6	African trypanosomiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
7	AGE-RAGE signaling pathway in diabetic complications 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
8	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
9	Allograft rejection 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
10	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
11	Alzheimer disease 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
12	Amoebiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
13	Amphetamine addiction 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
14	AMPK signaling pathway 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
15	AMPK signaling pathway 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
16	Amyotrophic lateral sclerosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
17	Amyotrophic lateral sclerosis 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
18	Antifolate resistance 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
19	Antifolate resistance 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
20	Autoimmune thyroid disease 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
21	Axon guidance 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
22	B cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
23	Bile secretion 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
24	Bile secretion 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
25	Bile secretion 💬	1件: NR1H4 💬	D09360 💬	Obeticholic acid	3件: 93, 265, 296 💬
26	Bile secretion 💬	1件: NR1H4 💬	D11548 💬	Tropifexor	1件: 93 💬
27	Bile secretion 💬	1件: NR1H4 💬	D00734 💬	Ursodeoxycholic acid	13件: 6 , 8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
28	Biosynthesis of cofactors 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
29	Biosynthesis of cofactors 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
30	Breast cancer 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
31	C-type lectin receptor signaling pathway 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
32	C-type lectin receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
33	Calcium signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
34	cAMP signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
35	cAMP signaling pathway 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
36	cAMP signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
37	cAMP signaling pathway 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
38	Cell adhesion molecules 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
39	Cellular senescence 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
40	cGMP-PKG signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
41	Chagas disease 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
42	Chagas disease 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
43	Chagas disease 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
44	Chemokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
45	Cholinergic synapse 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
46	Coronavirus disease - COVID-19 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
47	Coronavirus disease - COVID-19 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
48	Coronavirus disease - COVID-19 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
49	Coronavirus disease - COVID-19 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
50	Cytokine-cytokine receptor interaction 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
51	Cytokine-cytokine receptor interaction 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
52	Diabetic cardiomyopathy 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
53	Diabetic cardiomyopathy 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
54	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
55	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
56	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
57	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
58	Dopaminergic synapse 💬	3件: PPP3CA, PPP3CB, PPP3CC 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
59	Drug metabolism - other enzymes 💬	2件: IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
60	Drug metabolism - other enzymes 💬	2件: IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
61	Drug metabolism - other enzymes 💬	2件: IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
62	Drug metabolism - other enzymes 💬	2件: IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
63	EGFR tyrosine kinase inhibitor resistance 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
64	Epstein-Barr virus infection 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
65	Fat digestion and absorption 💬	1件: NPC1L1 💬	D01966 💬	Ezetimibe	4件: 49, 79, 93, 260 💬
66	Folate biosynthesis 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
67	Folate biosynthesis 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
68	Gap junction 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
69	Glucagon signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
70	Glucagon signaling pathway 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
71	Glucagon signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
72	Glucagon signaling pathway 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
73	Glucagon signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
74	Glutamatergic synapse 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
75	Graft-versus-host disease 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
76	Growth hormone synthesis, secretion and action 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
77	Hematopoietic cell lineage 💬	1件: MS4A1 💬	D02994 💬	Rituximab	47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
78	Hepatitis B 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
79	Hepatitis C 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
80	Hepatitis C 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
81	Hepatitis C 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
82	Hepatitis C 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
83	Hepatitis C 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
84	Herpes simplex virus 1 infection 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
85	Herpes simplex virus 1 infection 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
86	Human cytomegalovirus infection 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
87	Human cytomegalovirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
88	Human immunodeficiency virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
89	Human papillomavirus infection 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
90	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
91	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
92	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
93	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
94	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
95	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
96	Human T-cell leukemia virus 1 infection 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
97	Human T-cell leukemia virus 1 infection 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
98	Human T-cell leukemia virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
99	Huntington disease 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
100	Hypertrophic cardiomyopathy 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
101	Hypertrophic cardiomyopathy 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
102	Inflammatory bowel disease 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
103	Influenza A 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
104	Influenza A 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
105	Influenza A 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
106	Influenza A 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
107	Influenza A 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
108	Influenza A 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
109	Influenza A 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
110	Influenza A 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
111	Influenza A 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
112	Insulin resistance 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
113	Insulin resistance 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
114	Insulin resistance 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
115	Insulin resistance 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
116	Intestinal immune network for IgA production 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
117	JAK-STAT signaling pathway 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
118	JAK-STAT signaling pathway 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
119	Kaposi sarcoma-associated herpesvirus infection 💬	1件: CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
120	Kaposi sarcoma-associated herpesvirus infection 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
121	Kaposi sarcoma-associated herpesvirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
122	Legionellosis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
123	Leishmaniasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
124	Leishmaniasis 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
125	Long-term potentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
126	Malaria 💬	1件: IL12A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
127	MAPK signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
128	Measles 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
129	Measles 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
130	Metabolic pathways 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
131	Metabolic pathways 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
132	Metabolic pathways 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
133	Metabolic pathways 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
134	Metabolic pathways 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
135	Metabolic pathways 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
136	Metabolic pathways 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
137	Metabolic pathways 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
138	Metabolic pathways 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
139	Metabolic pathways 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
140	Metabolic pathways 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
141	Metabolic pathways 💬	2件: IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
142	Metabolic pathways 💬	2件: IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
143	Metabolic pathways 💬	2件: IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
144	Metabolic pathways 💬	2件: IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
145	Natural killer cell mediated cytotoxicity 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
146	Necroptosis 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
147	Neuroactive ligand-receptor interaction 💬	1件: NR3C1 💬	D00246 💬	Budesonide	9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
148	Neuroactive ligand-receptor interaction 💬	1件: NR3C1 💬	D00473 💬	Prednisone	47件: 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
149	NF-kappa B signaling pathway 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
150	NOD-like receptor signaling pathway 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
151	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
152	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
153	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
154	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
155	One carbon pool by folate 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
156	One carbon pool by folate 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
157	Oocyte meiosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
158	Osteoclast differentiation 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
159	Osteoclast differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
160	Osteoclast differentiation 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
161	Oxytocin signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
162	Pancreatic cancer 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
163	Parathyroid hormone synthesis, secretion and action 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
164	Parkinson disease 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
165	Pathogenic Escherichia coli infection 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
166	Pathways in cancer 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
167	Pathways in cancer 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
168	Pathways of neurodegeneration - multiple diseases 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
169	Pathways of neurodegeneration - multiple diseases 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
170	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
171	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
172	Pertussis 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
173	Phagosome 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
174	PI3K-Akt signaling pathway 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
175	PPAR signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
176	PPAR signaling pathway 💬	1件: PPARA 💬	D11208 💬	Elafibranor	1件: 93 💬
177	PPAR signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
178	PPAR signaling pathway 💬	1件: PPARA 💬	D10711 💬	Pemafibrate	1件: 93 💬
179	Prion disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
180	Prion disease 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
181	Prolactin signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
182	Prolactin signaling pathway 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
183	Proteoglycans in cancer 💬	1件: IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
184	Purine metabolism 💬	2件: IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
185	Purine metabolism 💬	2件: IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
186	Purine metabolism 💬	2件: IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	32件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
187	Purine metabolism 💬	2件: IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
188	Renin secretion 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
189	Renin secretion 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
190	Renin secretion 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
191	Renin-angiotensin system 💬	1件: ACE 💬	D00623 💬	Moexipril	1件: 93 💬
192	Renin-angiotensin system 💬	1件: ACE 💬	D08225 💬	Moexipril	1件: 93 💬
193	Rheumatoid arthritis 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
194	Rheumatoid arthritis 💬	1件: IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
195	Rheumatoid arthritis 💬	1件: TNFSF11 💬	D03684 💬	Denosumab	7件: 46, 50, 93, 95, 96, 274, 299 💬
196	RIG-I-like receptor signaling pathway 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
197	Salmonella infection 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	7件: 2 , 42, 46, 56, 93, 210, 266 💬
198	Signaling pathways regulating pluripotency of stem cells 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
199	Systemic lupus erythematosus 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
200	T cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
201	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D00942 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
202	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D03234 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
203	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D08484 💬	Risedronic acid	8件: 46, 50, 66, 93, 95, 96, 113, 274 💬
204	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D01968 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
205	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D06378 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
206	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D06379 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
207	Terpenoid backbone biosynthesis 💬	1件: FDPS 💬	D08689 💬	Zoledronic acid	10件: 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬
208	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
209	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
210	Th1 and Th2 cell differentiation 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
211	Th1 and Th2 cell differentiation 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
212	Th1 and Th2 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
213	Th17 cell differentiation 💬	1件: IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
214	Th17 cell differentiation 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
215	Th17 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
216	Toll-like receptor signaling pathway 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
217	Toll-like receptor signaling pathway 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
218	Toxoplasmosis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
219	Toxoplasmosis 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
220	Transcriptional misregulation in cancer 💬	1件: CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
221	Tuberculosis 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
222	Tuberculosis 💬	2件: JAK1, JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
223	Tuberculosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
224	Type I diabetes mellitus 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
225	Type I diabetes mellitus 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
226	VEGF signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
227	Viral carcinogenesis 💬	1件: JAK1 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
228	Viral myocarditis 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
229	Wnt signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬

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