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e.g. Sirolimus, Adalimumab

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70 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  1-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride  Piperazine  [6] D00807, D01393, D02127, D02145, D05486, D06224 💬  -  -  [1] 58 💬 
 2  Acamprosate  Acamprosate  [2] D02780, D07058 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [2]  6 , 206 💬 
 3  Amorphous calcium carbonate  Calcium  [2] D00932, D10802 💬  -  -  [1] 235 💬 
 4  Antimicrobial therapy: co-trimoxazole or doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 85 💬 
 5  Ascal(r) / carbasalate calcium  Calcium  [1] D03385 💬  -  -  [1] 46 💬 
 6  Atorvastatin  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 
 7  Atorvastatin 10mg  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 63 💬 
 8  Atorvastatin 20mg  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 63 💬 
 9  Atorvastatin calcium  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 265 💬 
 10  Atorvastatin tablet 20 mg  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 46 💬 
 11  Calcitriol & calcium  Calcitriol  [1] D00129 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1] 235 💬 
 12  Calcium  Calcium  -  -  -  [27]  6 , 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬 
 13  Calcium and cholecalciferol  Calcium  [1] D00188 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1] 46 💬 
 14  Calcium and vitamin d combination  Calcium  -  -  -  [1] 13 💬 
 15  Calcium carbonate  Calcium  [2] D00932, D10802 💬  -  -  [8] 13, 19, 46, 53, 75, 96, 235, 299 💬 
 16  Calcium carbonate and alphacalcidol  Calcium  [2] D00932, D10802 💬  -  -  [1] 235 💬 
 17  Calcium carbonate d  Calcium  [2] D00932, D10802 💬  -  -  [1] 53 💬 
 18  Calcium channel blockers  Calcium  -  -  -  [1] 51 💬 
 19  Calcium citrate  Calcium  [1] D00933 💬  -  -  [3] 46, 84, 235 💬 
 20  Calcium citrate with vitamin d2  Calcium  [2] D00187, D00933 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1] 84 💬 
 21  Calcium gluconate  Calcium  [1] D00935 💬  -  -  [3] 214, 215, 235 💬 
 22  Calcium lactate  Calcium  [2] D00936, D02254 💬  -  -  [1] 235 💬 
 23  Calcium levofolinate  Calcium  -  -  -  [1] 13 💬 
 24  Calcium rosuvastatin  Calcium  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 79 💬 
 25  Calcium, dietary  Calcium  -  -  -  [1] 298 💬 
 26  Carbasalate calcium  Calcium  [1] D03385 💬  -  -  [1] 46 💬 
 27  Crestor tablets (calcium rosuvastatin) film-coated tablets  Calcium  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 79 💬 
 28  Crystalline calcium supplements  Calcium  -  -  -  [1] 235 💬 
 29  Doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [15] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 162, 167, 227, 280, 299 💬 
 30  Doxycycline 100 mg capsules  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 89 💬 
 31  Doxycycline 100-200mg capsules daily for 6 months  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 167 💬 
 32  Doxycycline hyclate  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [3] 23, 96, 227 💬 
 33  Doxycycline hyclate ph.eur  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 167 💬 
 34  Doxycycline tablets  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 46 💬 
 35  Ethylhydrogenfumarat, calciumsalz  -  -  -  -  [1] 49 💬 
 36  Fosfomycin  Fosfomycin  [4] D00925, D02187, D02188, D04253 💬  -  -  [2] 96, 97 💬 
 37  Gabapentin  Gabapentin  [1] D00332 💬  [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬  [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [5]  6 , 13, 19, 70, 298 💬 
 38  Gabapentin prescriptions  Gabapentin  [1] D00332 💬  [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬  [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 298 💬 
 39  Ibandronate+alfacalcidol+calcium  Alfacalcidol  [2] D01518, D08056 💬  [2] FDPS, VDR 💬  [8] Endocrine and other factor-regulated calcium reabsorption, Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Terpenoid backbone biosynthesis, Tuberculosis  [1] 49 💬 
 40  Interferon beta 1a, oral doxycycline  Doxycycline  [6] D00307, D02129, D03903, D03904, D04554, D07876 💬  [2] IFNAR1, IFNAR2 💬  [18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway  [1] 13 💬 
 41  Interferon beta treatment to add-on atorvastatin treatment  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 13 💬 
 42  Interferon beta-1b/atorvastatin group  Atorvastatin  [4] D00258, D00746, D00887, D07474 💬  [3] HMGCR, IFNAR1, IFNAR2 💬  [22] AMPK signaling pathway, Bile secretion, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Terpenoid backbone biosynthesis, Toll-like receptor signaling pathway  [1] 13 💬 
 43  Isoniazid  Isoniazid  [3] D00346, D01501, D02002 💬  -  -  [1] 254 💬 
 44  Leucovorin  Leucovorin  [3] D01211, D07986, D07987 💬  -  -  [2] 19, 46 💬 
 45  Lisinopril, losartan, and atorvastatin  Atorvastatin  [7] D00258, D00357, D00362, D00887, D07474, D08131, D08146 💬  [3] ACE, AGTR1, HMGCR 💬  [22] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Bile secretion, Calcium signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Terpenoid backbone biosynthesis, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 222 💬 
 46  Low molecular weight heparin calcium injection  Calcium  [1] D07510 💬  [1] SERPINC1 💬  [1] Complement and coagulation cascades  [1] 224 💬 
 47  Methotrexate, leucovorin and bms-986142  BMS-986142  [5] D00142, D01211, D02115, D07986, D07987 💬  [2] DHFR, DHFR2 💬  [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [1] 46 💬 
 48  Multi-modal pain management [acetaminophen + gabapentin]  Acetaminophen  [2] D00217, D00332 💬  [7] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, PTGS1, PTGS2, SLC6A1 💬  [31] Adrenergic signaling in cardiomyocytes, Alzheimer disease, Arachidonic acid metabolism, Arrhythmogenic right ventricular cardiomyopathy, C-type lectin receptor signaling pathway, Cardiac muscle contraction, Chemical carcinogenesis, Dilated cardiomyopathy, GABAergic synapse, Human cytomegalovirus infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MAPK signaling pathway, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Synaptic vesicle cycle, TNF signaling pathway, VEGF signaling pathway  [1] 70 💬 
 49  Multi-modal pain management [valium + gabapentin]  Gabapentin  [1] D00332 💬  [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬  [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 70 💬 
 50  Mupirocin  Mupirocin  [2] D01076, D02195 💬  -  -  [2] 227, 299 💬 
 51  Mupirocin intranasal creme  Mupirocin  [2] D01076, D02195 💬  -  -  [1] 299 💬 
 52  Other: calcium stable isotope  Calcium  -  -  -  [1] 186 💬 
 53  Other: determination of calcium intake by a dietician interview  Calcium  -  -  -  [2] 13, 46 💬 
 54  Other: empiric use of calcium carbonate and calcitriol  Calcitriol  [3] D00129, D00932, D10802 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1] 235 💬 
 55  Other: no doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 299 💬 
 56  Other: pth based calcium carbonate and calcitriol repletion  Calcitriol  [3] D00129, D00932, D10802 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1] 235 💬 
 57  Other: serum calcium concentrations results  Calcium  -  -  -  [1] 235 💬 
 58  Piperazine  Piperazine  [6] D00807, D01393, D02127, D02145, D05486, D06224 💬  -  -  [1] 58 💬 
 59  Pitavastatin  Pitavastatin  [1] D01862 💬  -  -  [1] 49 💬 
 60  Rosuvastatin  Rosuvastatin  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 
 61  Rosuvastatin 10 mg  Rosuvastatin  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 96 💬 
 62  Rosuvastatin 20mg  Rosuvastatin  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 79 💬 
 63  Rosuvastatin calcium  Calcium  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [4] 49, 79, 97, 299 💬 
 64  Rosuvastatin calcium 40mg  Calcium  [2] D01915, D08492 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 56 💬 
 65  Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin)  Aldosterone  [3] D00150, D02014, D10528 💬  [3] AGTR1, AGTR2, NR3C2 💬  [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 222 💬 
 66  Transdermal fentanyl matrix, gabapentin  Fentanyl  [3] D00320, D00332, D01399 💬  [6] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, OPRM1, SLC6A1 💬  [12] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Estrogen signaling pathway, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 70 💬 
 67  Treatment with systemic therapy (doxycycline)  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  -  -  [1] 162 💬 
 68  Untreated to atorvastatin treatment  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 13 💬 
 69  Vidofludimus calcium  Calcium  -  -  -  [4] 13, 94, 96, 97 💬 
 70  Vidofludimus calcium dihydrate  Calcium  -  -  -  [1] 97 💬 

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