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55 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  5% lidocaine/5 mg/ml 0.02% estradiol compound cream  Estradiol  [11] D00105, D00358, D01413, D01617, D01953, D02086, D04061, D04063, D04064, D04065, D08127 💬  [7] ESR1, ESR2, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [12] Adrenergic signaling in cardiomyocytes, Breast cancer, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway  [1] 226 💬 
 2  A-dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 3  Alkalinized lidocaine-heparin  Heparin  [4] D00358, D02086, D07510, D08127 💬  [6] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SERPINC1 💬  [4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction  [1] 226 💬 
 4  Behavioral: role of dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 5  Bladder instillation with heparin/ lidocaine  Heparin  [4] D00358, D02086, D07510, D08127 💬  [6] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SERPINC1 💬  [4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction  [1] 226 💬 
 6  Bromocriptine and other dopamine agonists  Bromocriptine  [4] D00633, D00780, D03165, D07870 💬  [6] DRD1, DRD2, DRD3, DRD4, DRD5, PRL 💬  [15] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 7  Bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 
 8  Bupivacaine hydrochloride  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [2] 46, 53 💬 
 9  Bupivacaine hydrochloride 0.5% (marcaine, pfizer)  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 46 💬 
 10  Bupivacaine injection 0.5%  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 168 💬 
 11  Bupivacaine/epinephrine/dexamethasone  Bupivacaine  [14] D00095, D00292, D00975, D00996, D01450, D01510, D01615, D01632, D01948, D02149, D02174, D02591, D02592, D07552 💬  [15] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, NR3C1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 
 12  Ceftazidime  Ceftazidime  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 13  Ceftazidime and tobramycin  Ceftazidime  [4] D00063, D00921, D02542, D07654 💬  -  -  [1] 299 💬 
 14  Ceftazidime pentahydrate  Ceftazidime  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 15  Ceftazidime/avibactam  Avibactam  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 16  Ceftriaxone  Ceftriaxone  [2] D00924, D07659 💬  -  -  [3]  2 ,  6 , 97 💬 
 17  Cefuroxime  Cefuroxime  [4] D00262, D00914, D00915, D03431 💬  -  -  [2] 97, 299 💬 
 18  Cerebral dopamine neurotrophic factor  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 19  Clindamycin  Clindamycin  [4] D00277, D01073, D01990, D02132 💬  -  -  [2] 46, 299 💬 
 20  Conivaptan  Conivaptan  [2] D01236, D07748 💬  [2] AVPR1A, AVPR2 💬  [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption  [1] 86 💬 
 21  Continuous infusion ceftazidime  Ceftazidime  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 22  Continuous release dopamine agonists  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 23  Dextrose  Dextrose, unspecified form  -  -  -  [4] 56, 60, 65, 70 💬 
 24  Dextrose, 5% in water  Dextrose, unspecified form  [1] D00001 💬  -  -  [1] 65 💬 
 25  Dobutamine  Dobutamine  [4] D00632, D03879, D03880, D03881 💬  [1] ADRB1 💬  [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [3] 57, 58, 215 💬 
 26  Dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [3]  6 ,  7 , 74 💬 
 27  Dopamine agent  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 28  Dopamine agonist treatment  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1] 74 💬 
 29  Dopamine agonists  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1] 74 💬 
 30  Dopamine agonists (pramipexole, ropirinole)  Dopamine  [4] D00559, D00633, D05575, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 31  Ercp with bupivacaine infusion  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 298 💬 
 32  Heparin & alkalinized lidocaine bladder instillation  Heparin  [4] D00358, D02086, D07510, D08127 💬  [6] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SERPINC1 💬  [4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction  [1] 226 💬 
 33  Intermittent, short infusion ceftazidime  Ceftazidime  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 34  Iv ceftazidime  Ceftazidime  [2] D00921, D07654 💬  -  -  [1] 299 💬 
 35  Lap tap bupivacaine/epinephrine  Bupivacaine  [5] D00095, D00996, D01450, D02149, D07552 💬  [14] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 
 36  Lidocaine  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [10]  6 , 13, 34, 46, 51, 86, 168, 226, 231, 256 💬 
 37  Lidocaine 1% injectable solution  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 34 💬 
 38  Lidocaine 2% without vessel constrictor  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 51 💬 
 39  Lidocaine injection 2%  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 168 💬 
 40  Lidocaine patch 5%  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 13 💬 
 41  Lidocaine releasing intravesical system - liris®  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 226 💬 
 42  Liposomal bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3] 51, 70, 96 💬 
 43  Local anesthesia (lidocaine hydrochloride)  Lidocaine  [3] D00358, D02086, D08127 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1]  6  💬 
 44  Magnesium sulfate  Magnesium  [1] D01108 💬  -  -  [3] 11, 296, 297 💬 
 45  Nitroglycerin  Nitroglycerin  [1] D00515 💬  -  -  [1] 51 💬 
 46  Nitroglycerin ointment 2%  Nitroglycerin  [1] D00515 💬  -  -  [1] 51 💬 
 47  Other: dextrose water 5%  Dextrose, unspecified form  [1] D00001 💬  -  -  [1] 56 💬 
 48  Other: dobutamine  Dobutamine  [4] D00632, D03879, D03880, D03881 💬  [1] ADRB1 💬  [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 215 💬 
 49  Procedure: embryonic dopamine cell implant surgery  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 50  Prolotherapy solution of 20% dextrose  Dextrose, unspecified form  -  -  -  [1] 70 💬 
 51  Recombinant human cerebral dopamine neurotrophic factor  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 52  Spironolactone and conivaptan  Conivaptan  [3] D00443, D01236, D07748 💬  [3] AVPR1A, AVPR2, NR3C2 💬  [6] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption  [1] 86 💬 
 53  Topical amphimatrix with nitroglycerin (mqx-503)  Nitroglycerin  [1] D00515 💬  -  -  [1] 51 💬 
 54  Topical organogel with nitroglycerin  Nitroglycerin  [1] D00515 💬  -  -  [1] 51 💬 
 55  Us tap bupivacaine/epinephrine  Bupivacaine  [5] D00095, D00996, D01450, D02149, D07552 💬  [14] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 

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