Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	5% lidocaine/5 mg/ml 0.02% estradiol compound cream	Estradiol	[11] D00105, D00358, D01413, D01617, D01953, D02086, D04061, D04063, D04064, D04065, D08127 💬	[7] ESR1, ESR2, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[12] Adrenergic signaling in cardiomyocytes, Breast cancer, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway	[1] 226 💬
2	Estradiol	Estradiol	[8] D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[2] ESR1, ESR2 💬	[9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[5] 13, 46, 49, 226, 299 💬
3	Estradiol 2 mg	Estradiol	[8] D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[2] ESR1, ESR2 💬	[9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[1] 299 💬
4	Estradiol hemihydrate	Estradiol	[8] D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[2] ESR1, ESR2 💬	[9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[1] 13 💬
5	Ethinyl estradiol	Estradiol	[9] D00105, D00554, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[2] ESR1, ESR2 💬	[9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[3] 46, 49, 299 💬
6	Ethinylestradiol	Ethinylestradiol	[1] D00554 💬	[1] ESR1 💬	[8] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[1] 13 💬
7	Loestrin (norethindrone acetate and ethinyl estradiol)	Acetate	[11] D00105, D00182, D00554, D00953, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[3] ESR1, ESR2, PGR 💬	[11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[1] 299 💬
8	Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol)	Acetate	[11] D00105, D00182, D00554, D00953, D01413, D01617, D01953, D04061, D04063, D04064, D04065 💬	[3] ESR1, ESR2, PGR 💬	[11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[2] 46, 49 💬
9	Ortho-cyclen, ethinyl estradiol/norgestimate, 0.035 mg/0.250 mg	Estradiol	[10] D00105, D00554, D01413, D01617, D01953, D04061, D04063, D04064, D04065, D05209 💬	[3] ESR1, ESR2, PGR 💬	[11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway	[1] 299 💬