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e.g. Sirolimus, Adalimumab

ABCDEFGH I JKLMNOPQRSTUVWXYZother

69 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  100 mg elx /50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 2  100 mg elx/50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 3  100 mg elx/50 mg tez/75 mg iva fixed dose combination  -  -  -  -  [1] 299 💬 
 4  100 mg tez/150 mg iva fdc  -  -  -  -  [1] 299 💬 
 5  100 mg vx-445/50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 6  100-mg elx (vx-445) / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 7  100-mg elx (vx-455) / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 8  100-mg elx / 50-mg tez / 75 -mg iva fdc  -  -  -  -  [1] 299 💬 
 9  100-mg vx-445 / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 10  100-mg vx-445/50-mg tez/75-mg iva fdc  -  -  -  -  [1] 299 💬 
 11  100mg vx-445/50mg tez /75mg iva fdc  -  -  -  -  [1] 299 💬 
 12  150-mg ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 13  150mg ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 14  50 mg elx/25 mg tez/37.5 mg iva fixed dose combination  -  -  -  -  [1] 299 💬 
 15  Cf patients with a g551d mutation and treated with ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 16  Deuterated ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 17  Elexacaftor-tezacaftor-ivacaftor exposure  Elexacaftor  [3] D09916, D11041, D11507 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 18  Elx (vx-445)/tez (vx-661)/iva (vx-770)  -  -  -  -  [1] 299 💬 
 19  Elx/tez/iva  -  -  -  -  [1] 299 💬 
 20  Iva  -  -  -  -  [1] 299 💬 
 21  Iva 336  -  -  -  -  [1] 19 💬 
 22  Iva337  -  -  -  -  [1] 51 💬 
 23  Ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 24  Ivacaftor (proposed inn)  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 25  Ivacaftor 125mg tablet  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 26  Ivacaftor 150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 27  Ivacaftor 150 mg or 250 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 28  Ivacaftor 25 mg/75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 29  Ivacaftor 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 30  Ivacaftor 75 mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 31  Ivacaftor exposed  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 32  Ivacaftor or elexacaftor/tezacaftor/ivacaftor  Elexacaftor  [3] D09916, D11041, D11507 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 33  Ivacaftor+lumacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 34  Ivacaftor/ataluren  Ataluren  [2] D09323, D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 35  Ivacaftor/kalydeco  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 36  Lum/iva  -  -  -  -  [1] 299 💬 
 37  Lum/iva fixed-dose combination  -  -  -  -  [1] 299 💬 
 38  Lumacaftor / ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 39  Lumacaftor plus ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 40  Lumacaftor plus ivacaftor combination  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 41  Lumacaftor, ivacaftor drug combination  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 42  Lumacaftor-ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 43  Lumacaftor-ivacaftor treatment  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 44  Lumacaftor/ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 45  Lumacaftor/ivacaftor 100mg/125mg tablets  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 46  Lumacaftor/ivacaftor 200mg/125mg  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 47  Lumacaftor/ivacaftor 200mg/125mg tablets  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 48  Lumacaftor/ivacaftor 200mg/83mg tablet  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 49  Orkambi: contains lumacaftor and ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 50  Tez/iva  -  -  -  -  [1] 299 💬 
 51  Tezacaftor/ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 52  Tezacaftor/ivacaftor + ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 53  Tezacaftor/ivacaftor 100mg/150mg  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 54  Tezacaftor/ivacaftor/100mg/150mg  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 55  Vx-445 / tez / iva  -  -  -  -  [1] 299 💬 
 56  Vx-445 / tez / iva fdc  -  -  -  -  [1] 299 💬 
 57  Vx-445 /tez/iva  -  -  -  -  [1] 299 💬 
 58  Vx-445/tez/iva  -  -  -  -  [1] 299 💬 
 59  Vx-659/ tez/iva  VX-659  -  -  -  [1] 299 💬 
 60  Vx-659/tez/iva  VX-659  -  -  -  [1] 299 💬 
 61  Vx-659/tezacaftor/ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 62  Vx-661 plus ivacaftor combination  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 63  Vx-661/ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 64  Vx-661/ivacaftor (vx-770) 100mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 65  Vx-661/ivacaftor 100 mg/ 150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 66  Vx-661/ivacaftor 100mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 67  Vx-661/ivacaftor 100mg/150mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 68  Vx-661/ivacaftor 50 mg/ 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 69  Vx-661/vx-770 (tez/iva)  -  -  -  -  [1] 299 💬 

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