DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3	African trypanosomiasis 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[1] 107 💬
4	African trypanosomiasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
5	African trypanosomiasis 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
6	AGE-RAGE signaling pathway in diabetic complications 💬	[2] IL1A, IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
7	AGE-RAGE signaling pathway in diabetic complications 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
9	AGE-RAGE signaling pathway in diabetic complications 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
10	Allograft rejection 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬

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