Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
2 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
3 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
4 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
5 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
6 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
7 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
8 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
9 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
10 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
11 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
12 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
13 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
14 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
15 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
16 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
17 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
18 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
19 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
20 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
21 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
22 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
23 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
24 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
25 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
26 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
27 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
28 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
29 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
30 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
31 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
32 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
33 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
34 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
35 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
36 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
37 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
38 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
39 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [7] 13, 37, 41, 46, 160, 269, 271 💬 |
40 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
41 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
42 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
43 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
44 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
45 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
46 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
47 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
48 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
49 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
50 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
RARB [1] RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
51 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
52 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
53 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
54 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
55 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
56 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
57 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
58 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
59 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
60 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
61 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
62 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
63 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
64 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
65 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
66 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
67 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
68 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
69 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
70 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [7] 13, 37, 41, 46, 160, 269, 271 💬 |
71 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
72 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [7] 13, 37, 41, 46, 160, 269, 271 💬 |
73 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
74 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
75 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
76 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
77 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
78 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
79 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
80 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
81 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
82 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
83 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
84 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
85 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
86 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
87 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
88 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
89 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
90 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
91 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
92 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
93 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
94 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
95 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
96 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
97 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
98 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
99 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
100 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
101 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
RARB [1] RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
102 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
103 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
104 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
105 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
106 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
107 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
108 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
109 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
RARA [2] RARA, RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
110 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
111 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
112 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
113 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
114 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
115 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [6] 20, 93, 94, 160, 316, 324 💬 |
116 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
117 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
118 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
119 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
120 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
121 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [7] 13, 37, 41, 46, 160, 269, 271 💬 |
122 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
123 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
124 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
125 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
126 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
127 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
RARB [1] RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
128 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
129 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
130 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
131 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
132 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
133 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
134 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
135 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
136 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
137 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
138 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
139 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
140 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [7] 13, 37, 41, 46, 160, 269, 271 💬 |
141 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
142 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
143 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
144 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
145 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
146 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
147 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
148 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
149 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
150 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
151 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
152 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
153 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
154 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
155 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
156 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
157 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
158 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
159 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
160 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |