DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3	Alcoholism 💬	[1] DRD2 💬	D01164 💬	Aripiprazole	[2] 6 , 206 💬
4	Alcoholism 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5] 8 , 156, 179, 187, 206 💬
5	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D02780 💬	Acamprosate	[2] 6 , 206 💬
6	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D07058 💬	Acamprosate	[2] 6 , 206 💬
7	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
8	Alcoholism 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
9	Alcoholism 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
10	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D02780 💬	Acamprosate	[2] 6 , 206 💬

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