DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] RARA 💬	D01418 💬	Tamibarotene	[2] 26, 96 💬
2	Adipocytokine signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[7] 16, 26, 28, 34, 49, 284, 300 💬
3	African trypanosomiasis 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[7] 16, 26, 28, 34, 49, 284, 300 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[7] 16, 26, 28, 34, 49, 284, 300 💬
5	Alanine, aspartate and glutamate metabolism 💬	[4] ABAT, ALDH5A1, GAD1, GAD2 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
6	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
7	Allograft rejection 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[7] 16, 26, 28, 34, 49, 284, 300 💬
8	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬	D00481 💬	Propantheline	[1] 26 💬
9	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
10	Alzheimer disease 💬	[1] PSMB5 💬	D03150 💬	Bortezomib	[15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬

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