DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	African trypanosomiasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
2	African trypanosomiasis 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
3	AGE-RAGE signaling pathway in diabetic complications 💬	[2] IL1A, IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
5	Alzheimer disease 💬	[2] IL1A, IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
6	Alzheimer disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
7	Alzheimer disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	[7] 2 , 42, 46, 56, 93, 210, 266 💬
8	Amoebiasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
9	Amoebiasis 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
10	Amoebiasis 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬

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