DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
2	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3	Adipocytokine signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
4	Adipocytokine signaling pathway 💬	[1] TNF 💬	D02597 💬	Adalimumab	[16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
5	Adipocytokine signaling pathway 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[6] 37, 46, 96, 97, 226, 271 💬
6	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
7	Adipocytokine signaling pathway 💬	[1] TNF 💬	D04358 💬	Golimumab	[6] 46, 56, 84, 96, 97, 271 💬
8	Adipocytokine signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
9	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10	African trypanosomiasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬

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