DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
2	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
3	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
4	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
5	Alzheimer disease 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
6	Alzheimer disease 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
7	AMPK signaling pathway 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
8	AMPK signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
9	Amyotrophic lateral sclerosis 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
10	Amyotrophic lateral sclerosis 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬

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