Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00483 D00483 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
3 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [4] CHRM1, CHRM3, CHRM5, CHRNA7 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
4 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
5 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
6 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 [1] NR1H4 💬 |
D09360 D09360 💬 |
Obeticholic acid | 093 [3] 93, 265, 296 💬 |
7 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 [1] NR1H4 💬 |
D00734 D00734 💬 |
Ursodeoxycholic acid | 006 [13] 6 , 8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 |
8 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
SLC10A1 [2] SLC10A1, SLC10A2 💬 |
D10951 D10951 💬 |
Maralixibat | 296 [2] 296, 297 💬 |
9 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
SLC10A2 [1] SLC10A2 💬 |
D11716 D11716 💬 |
Odevixibat | 296 [1] 296 💬 |
10 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |