DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway💬 Info on mouse-over

A B C D E F G H I J K L M N O PQR S T U V WXYZother

78 / 286 pathways

entries per page:

Showing 1 to 10 of 159 entries

Filter by

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
2	Alanine, aspartate and glutamate metabolism 💬	[4] ABAT, ALDH5A1, GAD1, GAD2 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
3	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
4	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
5	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
6	Alzheimer disease 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
7	Alzheimer disease 💬	[1] PTGS2 💬	D00567 💬	Celecoxib	[9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬
8	Amphetamine addiction 💬	[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
9	Amyotrophic lateral sclerosis 💬	[7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
10	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬

First Previous1 2 3 4 5…16Next Last