DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
2	Acute myeloid leukemia 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[4] 13, 34, 89, 331 💬
3	Adherens junction 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
4	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
5	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[4] 13, 34, 89, 331 💬
6	Adipocytokine signaling pathway 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[6] 28, 34, 51, 85, 227, 331 💬
7	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
8	African trypanosomiasis 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
9	African trypanosomiasis 💬	[2] IL6, TNF 💬	D08976 💬	Pomalidomide	[6] 28, 34, 51, 85, 227, 331 💬
10	African trypanosomiasis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

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