DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] KIT 💬	D10229 💬	Masitinib	[6] 2 , 5 , 6 , 13, 46, 96 💬
2	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D01277 💬	Droxidopa	[3] 5 , 6 , 17 💬
3	Alanine, aspartate and glutamate metabolism 💬	[4] ABAT, ALDH5A1, GAD1, GAD2 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
4	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
5	Alcoholism 💬	[1] MAOB 💬	D02562 💬	Rasagiline	[6] 2 , 5 , 6 , 13, 17, 66 💬
6	Alcoholism 💬	[1] MAOB 💬	D08469 💬	Rasagiline	[6] 2 , 5 , 6 , 13, 17, 66 💬
7	Alcoholism 💬	[1] MAOB 💬	D10829 💬	Rasagiline	[6] 2 , 5 , 6 , 13, 17, 66 💬
8	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D00399 💬	Valproic acid	[16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
9	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬	D00787 💬	Trihexyphenidyl	[2] 5 , 6 💬
10	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬	D08638 💬	Trihexyphenidyl	[2] 5 , 6 💬

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