DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway💬 Info on mouse-over

A B C D E F G H I J K L M N O PQR S T U V WXYZother

65 / 286 pathways

entries per page:

Showing 1 to 10 of 123 entries

Filter by

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
4	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
5	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00986 💬	Fludrocortisone	[3] 6 , 17, 81 💬
6	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D07967 💬	Fludrocortisone	[3] 6 , 17, 81 💬
7	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
8	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
9	AMPK signaling pathway 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
10	AMPK signaling pathway 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬

First Previous1 2 3 4 5…13Next Last