DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
2	Breast cancer 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
3	cAMP signaling pathway 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
4	Cortisol synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
5	Cushing syndrome 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
6	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
7	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
8	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
9	GnRH secretion 💬	[1] ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
10	Hematopoietic cell lineage 💬	[1] MS4A1 💬	D02994 💬	Rituximab	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬

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