Target Gene/Pathway💬 Info on mouse-over

165 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
2 Adipocytokine signaling pathway 💬
[1] JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3 Adipocytokine signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
4 Adipocytokine signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
5 Adipocytokine signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
6 Adipocytokine signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
7 Adipocytokine signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8 Adipocytokine signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
9 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D00358 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
10 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D02086 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
11 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D08127 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
12 African trypanosomiasis 💬
[4] IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
13 African trypanosomiasis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
14 African trypanosomiasis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
15 African trypanosomiasis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
16 African trypanosomiasis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
17 African trypanosomiasis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
18 African trypanosomiasis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
[5] CCL2, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
20 AGE-RAGE signaling pathway in diabetic complications 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
21 AGE-RAGE signaling pathway in diabetic complications 💬
[1] JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
22 AGE-RAGE signaling pathway in diabetic complications 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
23 AGE-RAGE signaling pathway in diabetic complications 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
24 AGE-RAGE signaling pathway in diabetic complications 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
25 AGE-RAGE signaling pathway in diabetic complications 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
26 Alcoholism 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
27 Alcoholism 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
28 Alcoholism 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
29 Aldosterone synthesis and secretion 💬
[1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
30 Allograft rejection 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
31 Allograft rejection 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
32 Allograft rejection 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
33 Allograft rejection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
34 Allograft rejection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
35 Allograft rejection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
36 Allograft rejection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
37 Alzheimer disease 💬
[1] CHRNA7 💬 D03365 💬 Nicotine [2]  6 , 84 💬
38 Alzheimer disease 💬
[1] CHRNA7 💬 D05156 💬 Nicotine [2]  6 , 84 💬
39 Alzheimer disease 💬
[1] CHRNA7 💬 D05157 💬 Nicotine [2]  6 , 84 💬
40 Alzheimer disease 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
41 Alzheimer disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
42 Alzheimer disease 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
43 Alzheimer disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
44 Alzheimer disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
45 Alzheimer disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
46 Alzheimer disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
47 Amoebiasis 💬
[4] IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
48 Amoebiasis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
49 Amoebiasis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
50 Amoebiasis 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
51 Amoebiasis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
52 Amoebiasis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
53 Amoebiasis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
54 Amoebiasis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
55 Amphetamine addiction 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
56 Amphetamine addiction 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
57 Amphetamine addiction 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
58 AMPK signaling pathway 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
59 AMPK signaling pathway 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
60 AMPK signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
61 Amyotrophic lateral sclerosis 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
62 Amyotrophic lateral sclerosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
63 Amyotrophic lateral sclerosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
64 Amyotrophic lateral sclerosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
65 Amyotrophic lateral sclerosis 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
66 Amyotrophic lateral sclerosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
67 Antifolate resistance 💬
[2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
68 Antifolate resistance 💬
[2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
69 Antifolate resistance 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
70 Antifolate resistance 💬
[3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
71 Antifolate resistance 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
72 Antifolate resistance 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
73 Antifolate resistance 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
74 Antifolate resistance 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
75 Antigen processing and presentation 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
76 Antigen processing and presentation 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
77 Antigen processing and presentation 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
78 Antigen processing and presentation 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
79 Antigen processing and presentation 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
80 Apelin signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
81 Apoptosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
82 Apoptosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
83 Apoptosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
84 Apoptosis 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
85 Apoptosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
86 Asthma 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
87 Asthma 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
88 Asthma 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
89 Asthma 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
90 Asthma 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
91 Autoimmune thyroid disease 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
92 Autoimmune thyroid disease 💬
[1] IL10 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
93 Autophagy - animal 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
94 Autophagy - other 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
95 Bile secretion 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
96 Bile secretion 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
97 Bile secretion 💬
[1] NR1H4 💬 D00734 💬 Ursodeoxycholic acid [13]  6 ,  8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
98 Biosynthesis of cofactors 💬
[2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
99 Biosynthesis of cofactors 💬
[2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
100 Breast cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
101 C-type lectin receptor signaling pathway 💬
[4] IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
102 C-type lectin receptor signaling pathway 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
103 C-type lectin receptor signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
104 C-type lectin receptor signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
105 C-type lectin receptor signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
106 C-type lectin receptor signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
107 C-type lectin receptor signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
108 Calcium signaling pathway 💬
[1] CHRNA7 💬 D03365 💬 Nicotine [2]  6 , 84 💬
109 Calcium signaling pathway 💬
[1] CHRNA7 💬 D05156 💬 Nicotine [2]  6 , 84 💬
110 Calcium signaling pathway 💬
[1] CHRNA7 💬 D05157 💬 Nicotine [2]  6 , 84 💬
111 Calcium signaling pathway 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
112 Calcium signaling pathway 💬
[2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
113 Calcium signaling pathway 💬
[2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
114 cAMP signaling pathway 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
115 cAMP signaling pathway 💬
[1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
116 cAMP signaling pathway 💬
[1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
117 cAMP signaling pathway 💬
[1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
118 cAMP signaling pathway 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
119 cAMP signaling pathway 💬
[1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
120 cAMP signaling pathway 💬
[1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
121 Cell adhesion molecules 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
122 Cellular senescence 💬
[2] IL1A, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
123 Cellular senescence 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
124 Central carbon metabolism in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
125 cGMP-PKG signaling pathway 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
126 cGMP-PKG signaling pathway 💬
[2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
127 cGMP-PKG signaling pathway 💬
[2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
128 cGMP-PKG signaling pathway 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
129 cGMP-PKG signaling pathway 💬
[1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
130 Chagas disease 💬
[5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
131 Chagas disease 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
132 Chagas disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
133 Chagas disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
134 Chagas disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
135 Chagas disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
136 Chagas disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
137 Chemical carcinogenesis 💬
[1] CHRNA7 💬 D03365 💬 Nicotine [2]  6 , 84 💬
138 Chemical carcinogenesis 💬
[1] CHRNA7 💬 D05156 💬 Nicotine [2]  6 , 84 💬
139 Chemical carcinogenesis 💬
[1] CHRNA7 💬 D05157 💬 Nicotine [2]  6 , 84 💬
140 Chemokine signaling pathway 💬
[1] CCL2 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
141 Chemokine signaling pathway 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
142 Chemokine signaling pathway 💬
[2] JAK2, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
143 Choline metabolism in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
144 Cholinergic synapse 💬
[6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 D03365 💬 Nicotine [2]  6 , 84 💬
145 Cholinergic synapse 💬
[6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 D05156 💬 Nicotine [2]  6 , 84 💬
146 Cholinergic synapse 💬
[6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 D05157 💬 Nicotine [2]  6 , 84 💬
147 Cholinergic synapse 💬
[1] JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
148 Circadian entrainment 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
149 Cocaine addiction 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
150 Cocaine addiction 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
151 Cocaine addiction 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
152 Colorectal cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
153 Complement and coagulation cascades 💬
[1] SERPINC1 💬 D07510 💬 Heparin [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
154 Coronavirus disease - COVID-19 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
155 Coronavirus disease - COVID-19 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
156 Coronavirus disease - COVID-19 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
157 Coronavirus disease - COVID-19 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
158 Coronavirus disease - COVID-19 💬
[2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
159 Coronavirus disease - COVID-19 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
160 Coronavirus disease - COVID-19 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
161 Coronavirus disease - COVID-19 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
162 Coronavirus disease - COVID-19 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
163 Cortisol synthesis and secretion 💬
[1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
164 Cushing syndrome 💬
[1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
165 Cytokine-cytokine receptor interaction 💬
[6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
166 Cytokine-cytokine receptor interaction 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
167 Cytokine-cytokine receptor interaction 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
168 Cytokine-cytokine receptor interaction 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
169 Cytokine-cytokine receptor interaction 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
170 Cytokine-cytokine receptor interaction 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
171 Cytokine-cytokine receptor interaction 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
172 Cytokine-cytokine receptor interaction 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
173 Cytokine-cytokine receptor interaction 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
174 Cytokine-cytokine receptor interaction 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
175 Cytosolic DNA-sensing pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
176 Cytosolic DNA-sensing pathway 💬
[2] IL1B, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
177 Diabetic cardiomyopathy 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
178 Dilated cardiomyopathy 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
179 Dilated cardiomyopathy 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
180 Dilated cardiomyopathy 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
181 Dilated cardiomyopathy 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
182 Dilated cardiomyopathy 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
183 Dopaminergic synapse 💬
[1] SCN1A 💬 D00358 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
184 Dopaminergic synapse 💬
[1] SCN1A 💬 D02086 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
185 Dopaminergic synapse 💬
[1] SCN1A 💬 D08127 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
186 Dopaminergic synapse 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
187 Dopaminergic synapse 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
188 Dopaminergic synapse 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
189 Drug metabolism - other enzymes 💬
[2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
190 EGFR tyrosine kinase inhibitor resistance 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
191 EGFR tyrosine kinase inhibitor resistance 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
192 EGFR tyrosine kinase inhibitor resistance 💬
[2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
193 EGFR tyrosine kinase inhibitor resistance 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
194 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
195 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00187 💬 Ergocalciferol [5] 46, 84, 96, 97, 299 💬
196 Endocrine resistance 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
197 Endocytosis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
198 Epstein-Barr virus infection 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
199 Epstein-Barr virus infection 💬
[3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
200 Epstein-Barr virus infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
201 Epstein-Barr virus infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
202 Epstein-Barr virus infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
203 Epstein-Barr virus infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
204 ErbB signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
205 Fc epsilon RI signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
206 Fc epsilon RI signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
207 Fc epsilon RI signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
208 Fc epsilon RI signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
209 Fc epsilon RI signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
210 Fluid shear stress and atherosclerosis 💬
[4] CCL2, IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
211 Fluid shear stress and atherosclerosis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
212 Fluid shear stress and atherosclerosis 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
213 Fluid shear stress and atherosclerosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
214 Fluid shear stress and atherosclerosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
215 Fluid shear stress and atherosclerosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
216 Fluid shear stress and atherosclerosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
217 Folate biosynthesis 💬
[2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
218 Folate biosynthesis 💬
[2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
219 FoxO signaling pathway 💬
[2] IL10, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
220 GABAergic synapse 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
221 Gap junction 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
222 Gastric acid secretion 💬
[1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
223 Gastric acid secretion 💬
[1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
224 Gastric cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
225 Glioma 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
226 Graft-versus-host disease 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
227 Graft-versus-host disease 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
228 Graft-versus-host disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
229 Graft-versus-host disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
230 Graft-versus-host disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
231 Graft-versus-host disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
232 Graft-versus-host disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
233 Growth hormone synthesis, secretion and action 💬
[1] JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
234 Growth hormone synthesis, secretion and action 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
235 Growth hormone synthesis, secretion and action 💬
[1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
236 Growth hormone synthesis, secretion and action 💬
[1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
237 Hematopoietic cell lineage 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
238 Hematopoietic cell lineage 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
239 Hematopoietic cell lineage 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
240 Hematopoietic cell lineage 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
241 Hematopoietic cell lineage 💬
[1] MS4A1 💬 D02994 💬 Rituximab [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
242 Hematopoietic cell lineage 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
243 Hematopoietic cell lineage 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
244 Hematopoietic cell lineage 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
245 Hematopoietic cell lineage 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
246 Hepatitis B 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
247 Hepatitis B 💬
[4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
248 Hepatitis B 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
249 Hepatitis B 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
250 Hepatitis B 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
251 Hepatitis B 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
252 Hepatitis C 💬
[2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
253 Hepatitis C 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
254 Hepatitis C 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
255 Hepatitis C 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
256 Hepatitis C 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
257 Hepatitis C 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
258 Hepatocellular carcinoma 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
259 Herpes simplex virus 1 infection 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
260 Herpes simplex virus 1 infection 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
261 Herpes simplex virus 1 infection 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
262 Herpes simplex virus 1 infection 💬
[3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
263 Herpes simplex virus 1 infection 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
264 Herpes simplex virus 1 infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
265 Herpes simplex virus 1 infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
266 Herpes simplex virus 1 infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
267 Herpes simplex virus 1 infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
268 HIF-1 signaling pathway 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
269 HIF-1 signaling pathway 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
270 HIF-1 signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
271 Human cytomegalovirus infection 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
272 Human cytomegalovirus infection 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
273 Human cytomegalovirus infection 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
274 Human cytomegalovirus infection 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
275 Human cytomegalovirus infection 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
276 Human cytomegalovirus infection 💬
[1] JAK1 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
277 Human cytomegalovirus infection 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
278 Human cytomegalovirus infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
279 Human cytomegalovirus infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
280 Human cytomegalovirus infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
281 Human cytomegalovirus infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
282 Human immunodeficiency virus 1 infection 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
283 Human immunodeficiency virus 1 infection 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
284 Human immunodeficiency virus 1 infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
285 Human immunodeficiency virus 1 infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
286 Human immunodeficiency virus 1 infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
287 Human immunodeficiency virus 1 infection 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
288 Human immunodeficiency virus 1 infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
289 Human papillomavirus infection 💬
[2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
290 Human papillomavirus infection 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
291 Human papillomavirus infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
292 Human papillomavirus infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
293 Human papillomavirus infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
294 Human papillomavirus infection 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
295 Human papillomavirus infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
296 Human T-cell leukemia virus 1 infection 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
297 Human T-cell leukemia virus 1 infection 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
298 Human T-cell leukemia virus 1 infection 💬
[2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
299 Human T-cell leukemia virus 1 infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
300 Human T-cell leukemia virus 1 infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
301 Human T-cell leukemia virus 1 infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
302 Human T-cell leukemia virus 1 infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
303 Huntington disease 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
304 Hypertrophic cardiomyopathy 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
305 Hypertrophic cardiomyopathy 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
306 Hypertrophic cardiomyopathy 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
307 Hypertrophic cardiomyopathy 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
308 Hypertrophic cardiomyopathy 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
309 IL-17 signaling pathway 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
310 IL-17 signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
311 IL-17 signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
312 IL-17 signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
313 IL-17 signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
314 IL-17 signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
315 Inflammatory bowel disease 💬
[5] IL10, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
316 Inflammatory bowel disease 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
317 Inflammatory bowel disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
318 Inflammatory bowel disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
319 Inflammatory bowel disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
320 Inflammatory bowel disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
321 Inflammatory bowel disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
322 Inflammatory mediator regulation of TRP channels 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
323 Inflammatory mediator regulation of TRP channels 💬
[1] IL1B 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
324 Inflammatory mediator regulation of TRP channels 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
325 Influenza A 💬
[5] CCL2, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
326 Influenza A 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
327 Influenza A 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
328 Influenza A 💬
[3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
329 Influenza A 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
330 Influenza A 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
331 Influenza A 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
332 Influenza A 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
333 Insulin resistance 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
334 Insulin resistance 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
335 Insulin resistance 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
336 Insulin resistance 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
337 Insulin resistance 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
338 Insulin resistance 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
339 Insulin signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
340 Intestinal immune network for IgA production 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
341 Intestinal immune network for IgA production 💬
[2] IL10, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
342 JAK-STAT signaling pathway 💬
[2] IL10, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
343 JAK-STAT signaling pathway 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
344 JAK-STAT signaling pathway 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
345 JAK-STAT signaling pathway 💬
[4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
346 JAK-STAT signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
347 Kaposi sarcoma-associated herpesvirus infection 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
348 Kaposi sarcoma-associated herpesvirus infection 💬
[1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
349 Kaposi sarcoma-associated herpesvirus infection 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
350 Kaposi sarcoma-associated herpesvirus infection 💬
[3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
351 Kaposi sarcoma-associated herpesvirus infection 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
352 Legionellosis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
353 Legionellosis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
354 Legionellosis 💬
[3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
355 Legionellosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
356 Legionellosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
357 Legionellosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
358 Legionellosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
359 Leishmaniasis 💬
[4] IL10, IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
360 Leishmaniasis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
361 Leishmaniasis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
362 Leishmaniasis 💬
[2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
363 Leishmaniasis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
364 Leishmaniasis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
365 Leishmaniasis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
366 Leishmaniasis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
367 Long-term depression 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
368 Longevity regulating pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
369 Longevity regulating pathway - multiple species 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
370 Malaria 💬
[5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
371 Malaria 💬
[1] IL12A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
372 Malaria 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
373 Malaria 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
374 Malaria 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
375 Malaria 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
376 Malaria 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
377 MAPK signaling pathway 💬
[3] IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
378 MAPK signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
379 MAPK signaling pathway 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
380 MAPK signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
381 MAPK signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
382 MAPK signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
383 MAPK signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
384 Measles 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
385 Measles 💬
[3] IL1A, IL1B, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
386 Measles 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
387 Measles 💬
[3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
388 Melanogenesis 💬
[1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
389 Melanogenesis 💬
[1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
390 Metabolic pathways 💬
[2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
391 Metabolic pathways 💬
[2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
392 Metabolic pathways 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
393 Metabolic pathways 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
394 Metabolic pathways 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
395 Metabolic pathways 💬
[2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
396 Metabolic pathways 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
397 Metabolic pathways 💬
[1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
398 MicroRNAs in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
399 Mineral absorption 💬
[1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
400 Mineral absorption 💬
[1] VDR 💬 D00187 💬 Ergocalciferol [5] 46, 84, 96, 97, 299 💬
401 Morphine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
402 Morphine addiction 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
403 mTOR signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
404 mTOR signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
405 mTOR signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
406 mTOR signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
407 mTOR signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
408 mTOR signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
409 Natural killer cell mediated cytotoxicity 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
410 Natural killer cell mediated cytotoxicity 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
411 Natural killer cell mediated cytotoxicity 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
412 Natural killer cell mediated cytotoxicity 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
413 Natural killer cell mediated cytotoxicity 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
414 Necroptosis 💬
[3] IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
415 Necroptosis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
416 Necroptosis 💬
[4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
417 Necroptosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
418 Necroptosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
419 Necroptosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
420 Necroptosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
421 Neuroactive ligand-receptor interaction 💬
[16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬 D03365 💬 Nicotine [2]  6 , 84 💬
422 Neuroactive ligand-receptor interaction 💬
[16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬 D05156 💬 Nicotine [2]  6 , 84 💬
423 Neuroactive ligand-receptor interaction 💬
[16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬 D05157 💬 Nicotine [2]  6 , 84 💬
424 Neuroactive ligand-receptor interaction 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
425 Neuroactive ligand-receptor interaction 💬
[2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
426 Neuroactive ligand-receptor interaction 💬
[2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
427 Neuroactive ligand-receptor interaction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
428 Neuroactive ligand-receptor interaction 💬
[1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
429 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01703 💬 Ciclesonide [1] 84 💬
430 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00292 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
431 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00975 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
432 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01510 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
433 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01615 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
434 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01632 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
435 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01948 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
436 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D02174 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
437 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D02591 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
438 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D02592 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
439 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00407 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
440 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00751 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
441 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00979 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
442 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D05000 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
443 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D05001 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
444 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D05002 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
445 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00472 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
446 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00980 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
447 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00981 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
448 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00982 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
449 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01239 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
450 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D01998 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
451 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D02156 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
452 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D03301 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
453 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00473 💬 Prednisone [47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
454 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
455 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
456 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
457 Neuroactive ligand-receptor interaction 💬
[1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
458 Neuroactive ligand-receptor interaction 💬
[1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
459 Neutrophil extracellular trap formation 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
460 NF-kappa B signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
461 NF-kappa B signaling pathway 💬
[2] IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
462 NF-kappa B signaling pathway 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
463 NF-kappa B signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
464 NF-kappa B signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
465 NF-kappa B signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
466 NF-kappa B signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
467 Nicotine addiction 💬
[4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D03365 💬 Nicotine [2]  6 , 84 💬
468 Nicotine addiction 💬
[4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D05156 💬 Nicotine [2]  6 , 84 💬
469 Nicotine addiction 💬
[4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D05157 💬 Nicotine [2]  6 , 84 💬
470 Nicotine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
471 NOD-like receptor signaling pathway 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
472 NOD-like receptor signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
473 NOD-like receptor signaling pathway 💬
[2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
474 NOD-like receptor signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
475 NOD-like receptor signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
476 NOD-like receptor signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
477 NOD-like receptor signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
478 Non-alcoholic fatty liver disease 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
479 Non-alcoholic fatty liver disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
480 Non-alcoholic fatty liver disease 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
481 Non-alcoholic fatty liver disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
482 Non-alcoholic fatty liver disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
483 Non-alcoholic fatty liver disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
484 Non-alcoholic fatty liver disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
485 Non-small cell lung cancer 💬
[1] JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
486 One carbon pool by folate 💬
[2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
487 One carbon pool by folate 💬
[2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
488 Osteoclast differentiation 💬
[3] IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
489 Osteoclast differentiation 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
490 Osteoclast differentiation 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
491 Osteoclast differentiation 💬
[2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
492 Osteoclast differentiation 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
493 Osteoclast differentiation 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
494 Osteoclast differentiation 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
495 Osteoclast differentiation 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
496 Oxytocin signaling pathway 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
497 Pancreatic cancer 💬
[1] JAK1 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
498 Pancreatic cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
499 Parathyroid hormone synthesis, secretion and action 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
500 Parathyroid hormone synthesis, secretion and action 💬
[1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
501 Parathyroid hormone synthesis, secretion and action 💬
[1] VDR 💬 D00187 💬 Ergocalciferol [5] 46, 84, 96, 97, 299 💬
502 Parkinson disease 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
503 Parkinson disease 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
504 Parkinson disease 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
505 Pathogenic Escherichia coli infection 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
506 Pathogenic Escherichia coli infection 💬
[3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
507 Pathogenic Escherichia coli infection 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
508 Pathogenic Escherichia coli infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
509 Pathogenic Escherichia coli infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
510 Pathogenic Escherichia coli infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
511 Pathogenic Escherichia coli infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
512 Pathways in cancer 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
513 Pathways in cancer 💬
[2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
514 Pathways in cancer 💬
[2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
515 Pathways in cancer 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
516 Pathways in cancer 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
517 Pathways in cancer 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
518 Pathways in cancer 💬
[3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
519 Pathways in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
520 Pathways of neurodegeneration - multiple diseases 💬
[1] CHRNA7 💬 D03365 💬 Nicotine [2]  6 , 84 💬
521 Pathways of neurodegeneration - multiple diseases 💬
[1] CHRNA7 💬 D05156 💬 Nicotine [2]  6 , 84 💬
522 Pathways of neurodegeneration - multiple diseases 💬
[1] CHRNA7 💬 D05157 💬 Nicotine [2]  6 , 84 💬
523 Pathways of neurodegeneration - multiple diseases 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
524 Pathways of neurodegeneration - multiple diseases 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
525 Pathways of neurodegeneration - multiple diseases 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
526 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
527 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
528 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
529 Pathways of neurodegeneration - multiple diseases 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
530 Pathways of neurodegeneration - multiple diseases 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
531 Pathways of neurodegeneration - multiple diseases 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
532 Pathways of neurodegeneration - multiple diseases 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
533 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
[2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
534 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
535 Pertussis 💬
[5] IL10, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
536 Pertussis 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
537 Pertussis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
538 Pertussis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
539 Pertussis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
540 Pertussis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
541 Pertussis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
542 Phospholipase D signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
543 PI3K-Akt signaling pathway 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
544 PI3K-Akt signaling pathway 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
545 PI3K-Akt signaling pathway 💬
[3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
546 PI3K-Akt signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
547 Platelet activation 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
548 Platelet activation 💬
[1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
549 Platelet activation 💬
[1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
550 Platelet activation 💬
[1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
551 Primary immunodeficiency 💬
[1] JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
552 Prion disease 💬
[4] IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
553 Prion disease 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
554 Prion disease 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
555 Prion disease 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
556 Prion disease 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
557 Prion disease 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
558 Prolactin signaling pathway 💬
[1] JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
559 Prostate cancer 💬
[1] IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
560 Prostate cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
561 Proteoglycans in cancer 💬
[1] IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
562 Proteoglycans in cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
563 Proteoglycans in cancer 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
564 Proteoglycans in cancer 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
565 Proteoglycans in cancer 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
566 Proteoglycans in cancer 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
567 Proteoglycans in cancer 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
568 Purine metabolism 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
569 Purine metabolism 💬
[2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
570 Purine metabolism 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
571 Purine metabolism 💬
[1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
572 Relaxin signaling pathway 💬
[1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
573 Relaxin signaling pathway 💬
[1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
574 Renin secretion 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
575 Renin secretion 💬
[1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
576 Renin secretion 💬
[1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
577 Renin secretion 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
578 Retrograde endocannabinoid signaling 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
579 Rheumatoid arthritis 💬
[5] CCL2, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
580 Rheumatoid arthritis 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
581 Rheumatoid arthritis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
582 Rheumatoid arthritis 💬
[1] IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
583 Rheumatoid arthritis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
584 Rheumatoid arthritis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
585 Rheumatoid arthritis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
586 Rheumatoid arthritis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
587 RIG-I-like receptor signaling pathway 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
588 RIG-I-like receptor signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
589 RIG-I-like receptor signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
590 RIG-I-like receptor signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
591 RIG-I-like receptor signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
592 RIG-I-like receptor signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
593 Salivary secretion 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
594 Salmonella infection 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
595 Salmonella infection 💬
[3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
596 Salmonella infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
597 Salmonella infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
598 Salmonella infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
599 Salmonella infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
600 Serotonergic synapse 💬
[3] GABRB1, GABRB2, GABRB3 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
601 Shigellosis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
602 Shigellosis 💬
[2] IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
603 Shigellosis 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
604 Shigellosis 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
605 Shigellosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
606 Shigellosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
607 Shigellosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
608 Shigellosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
609 Signaling pathways regulating pluripotency of stem cells 💬
[3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
610 Sphingolipid signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
611 Sphingolipid signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
612 Sphingolipid signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
613 Sphingolipid signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
614 Sphingolipid signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
615 Spinocerebellar ataxia 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
616 Staphylococcus aureus infection 💬
[1] IL10 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
617 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
618 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
619 Synaptic vesicle cycle 💬
[1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
620 Systemic lupus erythematosus 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
621 Systemic lupus erythematosus 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
622 Systemic lupus erythematosus 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
623 Systemic lupus erythematosus 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
624 Systemic lupus erythematosus 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
625 Systemic lupus erythematosus 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
626 T cell receptor signaling pathway 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
627 T cell receptor signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
628 T cell receptor signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
629 T cell receptor signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
630 T cell receptor signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
631 Taste transduction 💬
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
632 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D00358 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
633 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D02086 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
634 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D08127 💬 Lidocaine [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
635 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
636 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
637 TGF-beta signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
638 TGF-beta signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
639 TGF-beta signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
640 TGF-beta signaling pathway 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
641 TGF-beta signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
642 Th1 and Th2 cell differentiation 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
643 Th1 and Th2 cell differentiation 💬
[4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
644 Th17 cell differentiation 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
645 Th17 cell differentiation 💬
[2] IL1B, IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
646 Th17 cell differentiation 💬
[1] IL1R1 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
647 Th17 cell differentiation 💬
[1] IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
648 Th17 cell differentiation 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
649 Th17 cell differentiation 💬
[4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
650 Th17 cell differentiation 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
651 Thermogenesis 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
652 Thyroid hormone signaling pathway 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
653 TNF signaling pathway 💬
[4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
654 TNF signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
655 TNF signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
656 TNF signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
657 TNF signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
658 TNF signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
659 Toll-like receptor signaling pathway 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
660 Toll-like receptor signaling pathway 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
661 Toll-like receptor signaling pathway 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
662 Toll-like receptor signaling pathway 💬
[3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
663 Toll-like receptor signaling pathway 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
664 Toll-like receptor signaling pathway 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
665 Toll-like receptor signaling pathway 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
666 Toll-like receptor signaling pathway 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
667 Toxoplasmosis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
668 Toxoplasmosis 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
669 Toxoplasmosis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
670 Toxoplasmosis 💬
[3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
671 Toxoplasmosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
672 Toxoplasmosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
673 Toxoplasmosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
674 Toxoplasmosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
675 Transcriptional misregulation in cancer 💬
[1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
676 Transcriptional misregulation in cancer 💬
[1] IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
677 Transcriptional misregulation in cancer 💬
[1] IL6 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
678 Tuberculosis 💬
[5] IL10, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
679 Tuberculosis 💬
[3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
680 Tuberculosis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
681 Tuberculosis 💬
[2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
682 Tuberculosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
683 Tuberculosis 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
684 Tuberculosis 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
685 Tuberculosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
686 Tuberculosis 💬
[1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
687 Tuberculosis 💬
[1] VDR 💬 D00187 💬 Ergocalciferol [5] 46, 84, 96, 97, 299 💬
688 Type I diabetes mellitus 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
689 Type I diabetes mellitus 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
690 Type I diabetes mellitus 💬
[3] IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
691 Type I diabetes mellitus 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
692 Type I diabetes mellitus 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
693 Type I diabetes mellitus 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
694 Type I diabetes mellitus 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
695 Type I diabetes mellitus 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
696 Type II diabetes mellitus 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
697 Type II diabetes mellitus 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
698 Type II diabetes mellitus 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
699 Type II diabetes mellitus 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
700 Type II diabetes mellitus 💬
[1] TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
701 Type II diabetes mellitus 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
702 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
703 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
704 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
705 Vascular smooth muscle contraction 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
706 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
707 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
708 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
709 Viral carcinogenesis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
710 Viral carcinogenesis 💬
[2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
711 Viral myocarditis 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
712 Viral protein interaction with cytokine and cytokine receptor 💬
[4] CCL2, IL10, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
713 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
714 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
715 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
716 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
717 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
718 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
719 Yersinia infection 💬
[5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
720 Yersinia infection 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
721 Yersinia infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
722 Yersinia infection 💬
[1] TNF 💬 D04358 💬 Golimumab [6] 46, 56, 84, 96, 97, 271 💬
723 Yersinia infection 💬
[1] TNF 💬 D02598 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
724 Yersinia infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬