DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	[1] PPARA 💬	D01366 💬	Bezafibrate	[6] 20, 93, 94, 160, 316, 324 💬
3	Adipocytokine signaling pathway 💬	[1] PPARA 💬	D11208 💬	Elafibranor	[1] 93 💬
4	Adipocytokine signaling pathway 💬	[1] PPARA 💬	D00565 💬	Fenofibrate	[5] 8 , 79, 93, 94, 265 💬
5	Adipocytokine signaling pathway 💬	[1] PPARA 💬	D10711 💬	Pemafibrate	[1] 93 💬
6	African trypanosomiasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
7	AGE-RAGE signaling pathway in diabetic complications 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
8	Allograft rejection 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
9	Allograft rejection 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
10	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬

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