DDrare: Database of Drug Development for Rare Diseases

Searched query = "Takayasu arteritis", "Aortitis syndrome", "Pulseless disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = AZA; Acetate; Adalimumab; Anti-thymocyte globulin; CYC; Clofarabine; Cyclophosphamide; Cyclosporine; DCB; Filgrastim; Glucocorticoids; INFLIXIMAB; Infliximab; Leflunomide; Leflunomide 10mg Tab; MMF; MTX; Methotrexate; Methotrexate Tablets; Methylprednisolone; Naltrexone; Naltrexone Hydrochloride; Placebo; Prednisolone; Prednisone; Prednisone Acetate; Prednisone acetate; Prednisone, cyclophosphamide; Procedure: Autologous Peripheral Blood Stem Cell Transplantation; Procedure: Computed Tomography; Procedure: Digital substraction angiography (DSA); Procedure: Drug coated balloon (DCB); Procedure: Positron Emission Tomography; Radiation: Fluorine F 18 Clofarabine; Remicade; Remicade (anti tumor necrosis factor inhibitor); RoActemra; RoActemra 20mg/ml; TOCILIZUMAB; Tocilizumab; Tocilizumab (MRA-SC); Tofacitinib; Tofacitinib tablet; Upadacitinib; Yellow Fever Vaccine; Yellow Fever vaccine (17D)

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04299971 (ClinicalTrials.gov)	March 1, 2020	5/3/2020	Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients	Randomized Open-label Study in Mild and Moderate Patients With Takayasu Arteritis Between Methotrexate and Tofacitinib Based on the ECTA Cohort.	Takayasu Arteritis;Methotrexate;Inhibition;Treatment	Drug: Methotrexate Tablets;Drug: Tofacitinib tablet	Shanghai Zhongshan Hospital	NULL	Recruiting	14 Years	100 Years	All	130	Phase 4	China
2	NCT03096275 (ClinicalTrials.gov)	March 16, 2017	13/3/2017	Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis	Comparison of the Efficacy of Mycophenolate Mofetil Combined With Methotrexate and Cyclophosphamide for the Treatment of Takayasu's Arteritis	Takayasu Arteritis	Drug: MMF;Drug: CYC;Drug: Glucocorticoids;Drug: MTX;Drug: AZA	Chinese SLE Treatment And Research Group	Peking Union Medical College Hospital	Recruiting	18 Years	N/A	All	150	Phase 3	China

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT04299971
(ClinicalTrials.gov)

March 1, 2020

5/3/2020

Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Randomized Open-label Study in Mild and Moderate Patients With Takayasu Arteritis Between Methotrexate and Tofacitinib Based on the ECTA Cohort.

Takayasu Arteritis;Methotrexate;Inhibition;Treatment

Drug: Methotrexate Tablets;Drug: Tofacitinib tablet

Shanghai Zhongshan Hospital

NULL

Recruiting

14 Years

100 Years

All

130

Phase 4

China

NCT03096275
(ClinicalTrials.gov)

March 16, 2017

13/3/2017

Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis

Comparison of the Efficacy of Mycophenolate Mofetil Combined With Methotrexate and Cyclophosphamide for the Treatment of Takayasu's Arteritis

Takayasu Arteritis

Drug: MMF;Drug: CYC;Drug: Glucocorticoids;Drug: MTX;Drug: AZA

Chinese SLE Treatment And Research Group

Peking Union Medical College Hospital

Recruiting

18 Years

N/A

All

150

Phase 3

China