Arct-810    (DrugBank: -)

1 disease
告示番号疾患名(ページ内リンク)臨床試験数
251尿素サイクル異常症2

251. 尿素サイクル異常症 [臨床試験数:42,薬物数:45(DrugBank:10),標的遺伝子数:4,標的パスウェイ数:29
Searched query = "Urea cycle disorder", "N-acetylglutamate synthase deficiency", "NAGS deficiency", "Carbamoyl phosphate synthetase I deficiency", "CPS1 deficiency", "Ornithine transcarbamylase deficiency", "OTC deficiency", "Classic citrullinemia", "Citrullinemia type I", "Argininosuccinic aciduria", "Argininemia", "Hiperornitinemia-hiperamonemia-homocitrulinuria syndrome", "HHH syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 42 trials found
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PhaseCountries
1NCT04442347
(ClinicalTrials.gov)
October 202019/6/2020Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase DeficiencyA Phase 1b Randomized, Double Blinded, Placebo Controlled, Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single Doses of ARCT-810 in Clinically Stable Patients With Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase DeficiencyBiological: ARCT-810;Other: PlaceboArcturus Therapeutics, Inc.NULLRecruiting18 YearsN/AAll12Phase 1United States
2NCT04416126
(ClinicalTrials.gov)
June 1, 202028/5/2020Safety, Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult SubjectsA Phase 1 Randomized, Double Blinded, Placebo Controlled, Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single Doses of ARCT-810 in Healthy Adult SubjectsOrnithine Transcarbamylase DeficiencyBiological: ARCT-810;Other: PlaceboArcturus Therapeutics, Inc.NULLRecruiting18 Years65 YearsAll30Phase 1New Zealand