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Histidine    (DrugBank: Histidine)

3 diseases
IDDisease name (Link within this page)Number of trials
13Multiple sclerosis/Neuromyelitis optica1
169Menkes disease4
170Occipital horn syndrome1

13. Multiple sclerosis/Neuromyelitis optica    [ 3,050 clinical trials,   2,147 drugs,   (DrugBank: 348 drugs),   244 drug target genes,   228 drug target pathways]
Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3,050 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT03266965
(ClinicalTrials.gov)		March 23, 20184/7/2017Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel ApproachHistaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel ApproachMultiple SclerosisDrug: Carbidopa;Dietary Supplement: L-HistidineUniversity of MiamiUnited States Department of DefenseCompleted18 Years60 YearsAll18Phase 1United States

169. Menkes disease    [ 6 clinical trials,   6 drugs,   (DrugBank: 3 drugs),   0 drug target gene,   0 drug target pathway]
Searched query = "Menkes disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
4 / 6 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1JPRN-UMIN000030626
2014/11/2828/12/2017Investigation on the effectiveness of histidine copper treatment of Menkes disease patients Menkes diseaseWeekly,subcutaneous injection of histidine copper (750microgram once) is performed three times per week.It is continued every week until the end of the research during the research period.Hamamatsu University School of MedicineNULLComplete: follow-up completeNot applicableNot applicableMale and Female2Not selectedJapan
2JPRN-UMIN000005259
2011/03/0318/03/2011Clinical trial of histidine-copper and diethyldithiocarbamate combination therapy for patients with Menkes disease Menkes diseasegive a dose of copper-histidine and diethyldithiocarbamateKobe Unniversitu Graduate School of MedicineNULLComplete: follow-up completeNot applicableNot applicableMale and Female2Not selectedJapan
3NCT00811785
(ClinicalTrials.gov)		February 27, 200918/12/2008Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper DeficiencyMolecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper DeficiencyMenkes Disease;Occipital Horn Syndrome;Unexplained Copper DeficiencyDrug: Copper HistidineCyprium Therapeutics, Inc.Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);National Center for Complementary and Integrative Health (NCCIH)CompletedN/A80 YearsAll93Phase 3United States
4NCT00001262
(ClinicalTrials.gov)		June 19903/11/1999Copper Histidine Therapy for Menkes DiseasesEarly Copper Histidine Therapy in Menkes DiseaseKinky Hair SyndromeDrug: Copper HistidineEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NULLCompletedN/AN/AAll60Phase 1;Phase 2United States

170. Occipital horn syndrome    [ 1 clinical trial,   3 drugs,   (DrugBank: 2 drugs),   0 drug target gene,   0 drug target pathway]
Searched query = "Occipital horn syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 1 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00811785
(ClinicalTrials.gov)		February 27, 200918/12/2008Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper DeficiencyMolecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper DeficiencyMenkes Disease;Occipital Horn Syndrome;Unexplained Copper DeficiencyDrug: Copper HistidineCyprium Therapeutics, Inc.Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);National Center for Complementary and Integrative Health (NCCIH)CompletedN/A80 YearsAll93Phase 3United States

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