DDrare: Database of Drug Development for Rare Diseases

Tretinoin (DrugBank: Tretinoin)

2 diseases

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	1
75	Cushing disease	1

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 508 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00919555 (ClinicalTrials.gov)	June 2008	8/6/2009	Combination Therapy in Amyotrophic Lateral Sclerosis (ALS)	Phase IIA Trial: Tretinoin and Pioglitazone HCL Combination Therapy in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	Drug: Pioglitazone and Tretinoin;Drug: Tretinoin and Pioglitazone HCL;Drug: Placebo	Phoenix Neurological Associates, LTD	NULL	Completed	18 Years	85 Years	Both	28	Phase 1;Phase 2	United States

75. Cushing disease [ 191 clinical trials, 172 drugs, (DrugBank: 48 drugs), 61 drug target genes, 121 drug target pathways]

Searched query = "Cushing disease", "Cushing"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 191 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2008-006379-65-IT (EUCTR)	27/10/2008	12/11/2008	Evaluation of the benefit-risk profile of retinoic acid in the treatment of Cushing`s disease - Retinoic acid in Cushing`s disease	Evaluation of the benefit-risk profile of retinoic acid in the treatment of Cushing`s disease - Retinoic acid in Cushing`s disease	sperimentation only in patients	INN or Proposed INN: Tretinoin	ISTITUTO AUXOLOGICO ITALIANO	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy