DDrare: Database of Drug Development for Rare Diseases

Amiodarone (DrugBank: Amiodarone)

2 diseases

ID	Disease name (Link within this page)	Number of trials
28	Systemic amyloidosis	1
127	Frontotemporal lobar degeneration	1

28. Systemic amyloidosis [ 212 clinical trials, 234 drugs, (DrugBank: 72 drugs), 54 drug target genes, 170 drug target pathways]

Searched query = "Systemic amyloidosis", "AL amyloidosis", "Immunoglobulin light chain amyloidosis", "Amyloid light-chain amyloidosis", "Familial amyloidosis", "Familial amyloid polyneuropathy", "Senile transthyretin amyloidosis", "Senile TTR amyloidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 212 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01511263 (ClinicalTrials.gov)	January 2012	10/1/2012	Epigallocatechingallate (EGCG) in Cardiac AL Amyloidosis	A Phase II Open-label Randomized Study of Dietary Supplement With Epigallocatechin Gallate (EGCG) to Improve Cardiac Dysfunction in Patients With AL Amyloidosis Who do Not Require Chemotherapy (EpiCardiAL)	Primary Amyloidosis of Light Chain Type	Drug: Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias);Drug: Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus EGCG	IRCCS Policlinico S. Matteo	NULL	Terminated	18 Years	N/A	All	86	Phase 2	Italy

127. Frontotemporal lobar degeneration [ 74 clinical trials, 83 drugs, (DrugBank: 28 drugs), 29 drug target genes, 99 drug target pathways]

Searched query = "Frontotemporal lobar degeneration", "Frontotemporal dementia", "Semantic dementia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 74 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-004571-37-IT (EUCTR)	21/02/2012	17/02/2012	Amiodarone therapy for treatment of fontotemporat dementia caused by progranulin deficiency	- Rescue of Progranulin HaploInsufficiency in Frontotemporal Dementia - ReProIn-FTD	frontotemporal dementia associated to progranulin deficit MedDRA version: 14.1;Level: SOC;Classification code 10029205;Term: Nervous system disorders;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	INN or Proposed INN: AMIODARONE Other descriptive name: NA	AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy