DDrare: Database of Drug Development for Rare Diseases

Thrombin (DrugBank: Thrombin)

2 diseases

ID	Disease name (Link within this page)	Number of trials
86	Pulmonary arterial hypertension	1
88	Chronic thromboembolic pulmonary hypertension	1

86. Pulmonary arterial hypertension [ 1,083 clinical trials, 667 drugs, (DrugBank: 122 drugs), 98 drug target genes, 185 drug target pathways]

Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 1,083 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03195543 (ClinicalTrials.gov)	March 12, 2015	8/6/2017	Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension	Assessment of Blood Coagulation Disorders in Patients With Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension.	Pulmonary Artery Hypertension;Chronic Thromboembolic Pulmonary Hypertension	Diagnostic Test: Platelet function analyzer-100;Diagnostic Test: Light transmission aggregometry;Diagnostic Test: Rotational thromboelastometry;Diagnostic Test: Endogenous thrombin potential	National and Kapodistrian University of Athens	NULL	Recruiting	18 Years	N/A	All	60		Greece

88. Chronic thromboembolic pulmonary hypertension [ 145 clinical trials, 112 drugs, (DrugBank: 22 drugs), 13 drug target genes, 52 drug target pathways]

Searched query = "Chronic thromboembolic pulmonary hypertension", "CTEPH", "Idiopathic chronic pulmonary thromboembolism"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 145 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03195543 (ClinicalTrials.gov)	March 12, 2015	8/6/2017	Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension	Assessment of Blood Coagulation Disorders in Patients With Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension.	Pulmonary Artery Hypertension;Chronic Thromboembolic Pulmonary Hypertension	Diagnostic Test: Platelet function analyzer-100;Diagnostic Test: Light transmission aggregometry;Diagnostic Test: Rotational thromboelastometry;Diagnostic Test: Endogenous thrombin potential	National and Kapodistrian University of Athens	NULL	Recruiting	18 Years	N/A	All	60		Greece