No. |
薬物名(臨床試験情報から抽出) |
DrugBank |
KEGG DRUG * |
KEGG GENES * |
KEGG PATHWAY |
指定難病告示番号 * |
1 |
1.2 mg zgn-440 for injectable suspension |
- |
- |
- |
- |
1件: 193 |
2 |
1.8 mg zgn-440 for injectable suspension |
- |
- |
- |
- |
1件: 193 |
3 |
Acomplia 20 mg film-coated tablets |
- |
- |
- |
- |
1件: 193 |
4 |
Acth |
Corticotropin |
D00146 |
1件: MC2R |
5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
5件: 13, 66, 145, 193, 222 |
5 |
Anastrozole |
Anastrozole |
D00960 |
1件: CYP19A1 |
3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis |
3件: 78, 86, 193 |
6 |
Azp-531 |
- |
- |
- |
- |
1件: 193 |
7 |
B. lactis b94 |
- |
- |
- |
- |
1件: 193 |
8 |
Beloranib |
Beloranib |
- |
- |
- |
1件: 193 |
9 |
Byetta |
Exenatide |
D04121 |
1件: GLP1R |
3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
1件: 193 |
10 |
Cannabidiol |
Cannabidiol |
D10915 |
2件: CNR1, CNR2 |
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis |
13件: 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
11 |
Cannabidiol oral solution |
Cannabidiol |
D10915 |
2件: CNR1, CNR2 |
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis |
4件: 140, 144, 145, 193 |
12 |
Carbetocin |
Carbetocin |
D07229 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
13 |
Cbdv |
Cannabidivarin |
- |
- |
- |
1件: 193 |
14 |
Cbdv compound |
Cannabidivarin |
- |
- |
- |
1件: 193 |
15 |
Chloride |
Chloride ion |
- |
- |
- |
17件: 6, 11, 13, 14, 34, 46, 51, 96, 97, 127, 168, 193, 227, 228, 288, 297, 299 |
16 |
Choline |
Choline |
D07690 |
- |
- |
4件: 65, 171, 193, 299 |
17 |
Coenzyme q10 |
Ubidecarenone |
D01065 |
- |
- |
10件: 2, 6, 8, 10, 46, 57, 113, 193, 214, 215 |
18 |
Dccr |
- |
- |
- |
- |
1件: 193 |
19 |
Diazoxide |
Diazoxide |
D00294 |
2件: ABCC8, KCNJ11 |
4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus |
1件: 193 |
20 |
Diazoxide choline controlled-release tablet |
Diazoxide |
D00294 |
2件: ABCC8, KCNJ11 |
4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus |
1件: 193 |
21 |
Eu/1/06/362/003: 5µg (1 pen) |
- |
- |
- |
- |
1件: 193 |
22 |
Eutropin |
- |
- |
- |
- |
2件: 78, 193 |
23 |
Exenatide |
Exenatide |
D04121 |
1件: GLP1R |
3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
3件: 6, 193, 233 |
24 |
Fe 992097 |
- |
- |
- |
- |
1件: 193 |
25 |
Genotonorm |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
1件: 193 |
26 |
Genotonorm miniquick 0,2 mg |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
1件: 193 |
27 |
Genotropin |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
3件: 13, 78, 193 |
28 |
Genotropin (somatropin) is a growth hormone treatment. it is an exact copy of the natural growth hormone that our bodies make. the main difference is that genotropin is man-made. |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
1件: 193 |
29 |
Glwl-01 |
- |
- |
- |
- |
1件: 193 |
30 |
Growth hormone |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
11件: 2, 13, 19, 46, 78, 96, 191, 193, 195, 265, 299 |
31 |
Growth hormone (genotonorm® or omnitrope®) |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
2件: 78, 193 |
32 |
Guanfacine |
Guanfacine |
D00606, D08031 |
1件: ADRA2A |
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
1件: 193 |
33 |
Guanfacine extended release (gxr) |
Guanfacine |
D00606, D08031 |
1件: ADRA2A |
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
1件: 193 |
34 |
Human growth hormone |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
3件: 78, 193, 265 |
35 |
Humatrope 6 mg/12 mg/24 mg injektiokuiva-aine ja liuotin, liuosta varten |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
1件: 193 |
36 |
Inn not yet proposed |
- |
- |
- |
- |
1件: 193 |
37 |
Intranasal carbetocin dose 1 |
Carbetocin |
D07229 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
38 |
Intranasal carbetocin dose 2 |
Carbetocin |
D07229 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
39 |
Intranasal oxytocin |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
2件: 127, 193 |
40 |
Intranasal oxytocin (in-oxt) |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
41 |
Liraglutide |
Liraglutide |
D06404 |
1件: GLP1R |
3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
3件: 6, 75, 193 |
42 |
Livoletide |
Livoletide |
- |
- |
- |
1件: 193 |
43 |
Medical air |
Medical air |
- |
- |
- |
3件: 85, 86, 193 |
44 |
Medical air vs oxygen |
Medical air |
- |
- |
- |
1件: 193 |
45 |
Metoprolol |
Metoprolol |
D00601, D02358, D05011 |
1件: ADRB1 |
10件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
6件: 17, 57, 58, 113, 193, 226 |
46 |
Metoprolol succinate |
Metoprolol |
D00601, D02358, D05011 |
1件: ADRB1 |
10件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
4件: 57, 58, 113, 193 |
47 |
Metoprololsuccinat orion 25mg |
- |
- |
- |
- |
1件: 193 |
48 |
Metoprololsuccinat ”orion” 25mg |
- |
- |
- |
- |
1件: 193 |
49 |
Metyrapone |
Metyrapone |
D00410, D05019 |
1件: CYP11B1 |
4件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis |
2件: 75, 193 |
50 |
Norditropin simplexx |
- |
- |
- |
- |
4件: 3, 78, 193, 195 |
51 |
Nutropin aq |
- |
- |
- |
- |
4件: 78, 134, 193, 299 |
52 |
Octreotide |
Octreotide |
D00442, D06495 |
1件: SSTR2 |
4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
7件: 67, 75, 84, 85, 89, 193, 227 |
53 |
Omnitrope |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
2件: 78, 193 |
54 |
Oxygen |
Oxygen |
D00003 |
- |
- |
14件: 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 299, 330 |
55 |
Oxytocin |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
4件: 127, 193, 206, 226 |
56 |
Oxytocin (oxt) continuous |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
57 |
Physiological serum (sodium chloride) |
Sodium chloride |
D02056 |
- |
- |
1件: 193 |
58 |
Probiotic |
- |
- |
- |
- |
5件: 2, 6, 96, 193, 266 |
59 |
Recombinant human growth hormon |
- |
- |
- |
- |
1件: 193 |
60 |
Recombinant human growth hormone |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
3件: 78, 193, 265 |
61 |
Recombinant somatropin |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
1件: 193 |
62 |
Rimonabant |
Rimonabant |
D05731 |
1件: CNR1 |
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis |
1件: 193 |
63 |
Rm-493 |
- |
- |
- |
- |
1件: 193 |
64 |
Sandostatin lar |
- |
- |
- |
- |
4件: 67, 84, 193, 227 |
65 |
Saxenda |
Liraglutide |
D06404 |
1件: GLP1R |
3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway |
1件: 193 |
66 |
Sodium chloride |
Sodium chloride |
D02056 |
- |
- |
13件: 6, 11, 13, 14, 34, 46, 51, 168, 193, 227, 228, 288, 299 |
67 |
Somatropin |
Somatotropin |
D02691 |
1件: GHR |
5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway |
15件: 2, 3, 19, 46, 74, 75, 78, 96, 113, 193, 195, 265, 274, 276, 299 |
68 |
Subcutaneous beloranib in suspension |
Beloranib |
- |
- |
- |
1件: 193 |
69 |
Syntocinon |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
2件: 127, 193 |
70 |
Syntocinon nasal spray |
Oxytocin |
D00089 |
1件: OXTR |
4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
1件: 193 |
71 |
Syntocinon®/- spray |
- |
- |
- |
- |
1件: 193 |
72 |
Tesofensine |
Tesofensine |
- |
- |
- |
2件: 6, 193 |
73 |
Tesofensine/metoprolol |
Tesofensine |
- |
- |
- |
1件: 193 |
74 |
Topiramate |
Topiramate |
D00537 |
36件: CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
48件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
5件: 6, 140, 144, 156, 193 |
75 |
Zgn-440 |
- |
- |
- |
- |
1件: 193 |
76 |
Zgn-440 for injectable suspension |
- |
- |
- |
- |
1件: 193 |
77 |
Zgn-440 sterile diluent |
- |
- |
- |
- |
1件: 193 |