No. |
薬物名(臨床試験情報から抽出) |
DrugBank |
KEGG DRUG * |
KEGG GENES * |
KEGG PATHWAY |
指定難病告示番号 * |
1 |
18f-av-1451 |
Flortaucipir f-18 |
- |
- |
- |
3件: 5, 7, 127 |
2 |
18f-ro6958948 |
- |
- |
- |
- |
3件: 5, 7, 127 |
3 |
4-benzyl-2-naphtalen-1-yl-1,2,4-thiadiazolidine-3,5-dione |
- |
- |
- |
- |
1件: 5 |
4 |
[18f]florbetapir |
- |
- |
- |
- |
1件: 5 |
5 |
[18f]mni-815 (mni-815) |
- |
- |
- |
- |
1件: 5 |
6 |
[18f]mni-952 |
- |
- |
- |
- |
1件: 5 |
7 |
[18f]mni-958 |
- |
- |
- |
- |
1件: 5 |
8 |
[18f]t807 ([18f]mni-777) |
- |
- |
- |
- |
2件: 5, 6 |
9 |
[f18]-fddnp |
- |
- |
- |
- |
1件: 5 |
10 |
Ab1010 |
Masitinib |
D10229 |
1件: KIT |
11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
6件: 2, 5, 6, 13, 46, 96 |
11 |
Abbv-8e12 |
- |
- |
- |
- |
2件: 5, 7 |
12 |
Al-108 |
- |
- |
- |
- |
1件: 5 |
13 |
Alpha-lipoic acid and l-acetyl carnitine |
Lipoic acid |
D00048, D00086 |
- |
- |
1件: 5 |
14 |
Anti-parkinson medication |
- |
- |
- |
- |
4件: 5, 6, 7, 17 |
15 |
Ask nr. 21972 |
- |
- |
- |
- |
1件: 5 |
16 |
Azilect |
Rasagiline |
D02562, D08469, D10829 |
1件: MAOB |
13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism |
3件: 5, 6, 17 |
17 |
Azp2006 oral solution |
- |
- |
- |
- |
1件: 5 |
18 |
Balance |
Isoxaflutole |
- |
- |
- |
8件: 5, 6, 13, 18, 81, 113, 149, 299 |
19 |
Biib092 |
- |
- |
- |
- |
3件: 5, 7, 127 |
20 |
Botulinum toxin type a |
Botulinum toxin type a |
D00783 |
1件: SNAP25 |
2件: Insulin secretion, Synaptic vesicle cycle |
10件: 2, 5, 6, 7, 13, 15, 17, 70, 113, 149 |
21 |
Carnitine |
Levocarnitine |
D02030, D02176, D04713 |
- |
- |
8件: 5, 13, 58, 96, 97, 265, 298, 316 |
22 |
Coenzym q10 nanodispersion |
- |
- |
- |
- |
1件: 5 |
23 |
Coenzym q10, ubiquinon, ubichinon |
- |
- |
- |
- |
1件: 5 |
24 |
Coenzymeq10 |
- |
- |
- |
- |
2件: 5, 21 |
25 |
Coq10 |
Ubidecarenone |
D01065 |
- |
- |
3件: 5, 6, 8 |
26 |
Creatine |
Creatine |
- |
- |
- |
12件: 1, 2, 5, 6, 8, 13, 46, 49, 50, 113, 156, 201 |
27 |
Datscan |
Ioflupane i-123 |
D10014 |
- |
- |
3件: 2, 5, 6 |
28 |
Davunetide |
Davunetide |
D09401 |
- |
- |
3件: 5, 7, 127 |
29 |
Davunetide (al-108, nap) |
Davunetide |
D09401 |
- |
- |
3件: 5, 7, 127 |
30 |
Donepezil |
Donepezil |
D00670, D07869 |
1件: ACHE |
2件: Cholinergic synapse, Glycerophospholipid metabolism |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
31 |
Droxidopa |
Droxidopa |
D01277 |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
3件: 5, 6, 17 |
32 |
Exelon 1,5 mg hartkapseln |
Rivastigmine |
D02558, D03822 |
1件: ACHE |
2件: Cholinergic synapse, Glycerophospholipid metabolism |
1件: 5 |
33 |
Exelon 3,0 mg hartkapseln |
Rivastigmine |
D02558, D03822 |
1件: ACHE |
2件: Cholinergic synapse, Glycerophospholipid metabolism |
1件: 5 |
34 |
Exelon 6,0 mg hartkapseln |
Rivastigmine |
D02558, D03822 |
1件: ACHE |
2件: Cholinergic synapse, Glycerophospholipid metabolism |
1件: 5 |
35 |
F-18 |
- |
- |
- |
- |
2件: 5, 127 |
36 |
F-18 av 1451 |
- |
- |
- |
- |
1件: 5 |
37 |
Florbetapir f18 |
- |
- |
- |
- |
2件: 5, 7 |
38 |
Flutemetamol |
Flutemetamol |
- |
- |
- |
5件: 5, 6, 7, 17, 127 |
39 |
Fresh frozen plasma |
- |
- |
- |
- |
1件: 5 |
40 |
Gdnf & synchro med infusion system |
- |
- |
- |
- |
1件: 5 |
41 |
Hydrogen |
Hydrogen |
- |
- |
- |
5件: 5, 6, 17, 97, 226 |
42 |
Leucine |
L-leucine |
D00030 |
- |
- |
7件: 5, 6, 7, 127, 283, 284, 299 |
43 |
Lipoic acid |
Lipoic acid |
D00048, D00086 |
- |
- |
5件: 2, 5, 13, 14, 20 |
44 |
Lithium |
Lithium citrate |
D04749 |
- |
- |
4件: 2, 5, 7, 8 |
45 |
Masitinib |
Masitinib |
D10229 |
1件: KIT |
11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
6件: 2, 5, 6, 13, 46, 96 |
46 |
Masitinib 100mg |
Masitinib |
D10229 |
1件: KIT |
11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
1件: 5 |
47 |
Masitinib 200mg |
Masitinib |
D10229 |
1件: KIT |
11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
1件: 5 |
48 |
Masitinib mesylate |
Masitinib |
D10229 |
1件: KIT |
11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
6件: 2, 5, 6, 13, 46, 96 |
49 |
Niacinamide |
Nicotinamide |
D00036 |
- |
- |
4件: 5, 6, 13, 67 |
50 |
Nitrogen |
Nitrogen |
D00083 |
- |
- |
5件: 5, 6, 17, 211, 299 |
51 |
Np031112 |
- |
- |
- |
- |
1件: 5 |
52 |
Np031112 600mg |
- |
- |
- |
- |
1件: 5 |
53 |
Np031112 800mg |
- |
- |
- |
- |
1件: 5 |
54 |
Nt 101 |
- |
- |
- |
- |
4件: 5, 6, 7, 17 |
55 |
Pyruvate, creatine, niacinamide |
Creatine |
- |
- |
- |
1件: 5 |
56 |
Raclopride |
Raclopride |
- |
- |
- |
4件: 5, 6, 7, 17 |
57 |
Radiopharmaceuticals |
- |
- |
- |
- |
1件: 5 |
58 |
Rasagilin |
- |
- |
- |
- |
2件: 5, 6 |
59 |
Rasagiline |
Rasagiline |
D02562, D08469, D10829 |
1件: MAOB |
13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism |
4件: 2, 5, 6, 17 |
60 |
Rasagiline mesilate |
Rasagiline |
D02562, D08469, D10829 |
1件: MAOB |
13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism |
3件: 2, 5, 6 |
61 |
Riluzole |
Riluzole |
D00775 |
14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway |
7件: 2, 3, 5, 8, 13, 17, 206 |
62 |
Rivastigmine |
Rivastigmine |
D02558, D03822 |
1件: ACHE |
2件: Cholinergic synapse, Glycerophospholipid metabolism |
3件: 5, 6, 13 |
63 |
Salsalate |
Salsalate |
D00428 |
2件: PTGS1, PTGS2 |
21件: Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway |
1件: 5 |
64 |
Single dose c2n-8e12 |
- |
- |
- |
- |
1件: 5 |
65 |
Stem cell therapy |
- |
- |
- |
- |
1件: 5 |
66 |
Suvorexant |
Suvorexant |
D10082 |
2件: HCRTR1, HCRTR2 |
1件: Neuroactive ligand-receptor interaction |
3件: 5, 6, 13 |
67 |
Tideglusib |
Tideglusib |
- |
- |
- |
2件: 5, 113 |
68 |
Tpi 287 2 mg/m2 |
- |
- |
- |
- |
2件: 5, 7 |
69 |
Tpi-287 20 mg/m2 |
- |
- |
- |
- |
2件: 5, 7 |
70 |
Tpi-287 6.3 mg/m2 |
- |
- |
- |
- |
2件: 5, 7 |
71 |
Trihexyphenidyl |
Trihexyphenidyl |
D00787, D08638 |
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
11件: Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway |
2件: 5, 6 |
72 |
Ubidecarenon |
- |
- |
- |
- |
1件: 5 |
73 |
Valproic acid |
Valproic acid |
D00399 |
7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 |
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism |
10件: 3, 5, 26, 34, 65, 89, 90, 222, 256, 331 |
74 |
Vizamyl |
- |
- |
- |
- |
3件: 5, 7, 127 |
75 |
Vizamyl (flutemetamol(f-18)) |
Flutemetamol |
- |
- |
- |
3件: 5, 7, 127 |
76 |
Water |
Water |
D00001 |
- |
- |
18件: 2, 5, 6, 13, 17, 19, 35, 46, 53, 57, 63, 65, 67, 84, 97, 226, 278, 299 |
77 |
Xeomin |
Botulinum toxin type a |
D00783 |
1件: SNAP25 |
2件: Insulin secretion, Synaptic vesicle cycle |
7件: 5, 6, 7, 13, 15, 17, 113 |
78 |
Zolpidem |
Zolpidem |
D00706, D08690 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction |
2件: 5, 6 |