No. |
薬物名(臨床試験情報から抽出) |
DrugBank |
KEGG DRUG * |
KEGG GENES * |
KEGG PATHWAY |
指定難病告示番号 * |
1 |
Abiraterone |
Abiraterone |
D09701 |
- |
- |
2件: 75, 81 |
2 |
Abiraterone acetate |
Abiraterone |
D09701 |
- |
- |
2件: 75, 81 |
3 |
Acetate |
Acetate |
- |
- |
- |
40件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 70, 71, 73, 75, 76, 78, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 235, 265, 288, 298, 299 |
4 |
Atr-101 |
- |
- |
- |
- |
2件: 75, 81 |
5 |
Balance |
Isoxaflutole |
- |
- |
- |
8件: 5, 6, 13, 18, 81, 113, 149, 299 |
6 |
Bone balance measurements |
Isoxaflutole |
- |
- |
- |
1件: 81 |
7 |
Chronocort |
- |
- |
- |
- |
1件: 81 |
8 |
Chronocort® |
- |
- |
- |
- |
1件: 81 |
9 |
Chronocort® 10 mg |
- |
- |
- |
- |
1件: 81 |
10 |
Chronocort® 20 mg |
- |
- |
- |
- |
1件: 81 |
11 |
Chronocort® 5 mg |
- |
- |
- |
- |
1件: 81 |
12 |
Ci-984, 17aa70, pd 132301-2 |
- |
- |
- |
- |
1件: 81 |
13 |
Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone) |
Cortisone acetate |
D00973 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
14 |
Cortef |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
2件: 81, 83 |
15 |
Cortisol |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
16 |
Cortison |
- |
- |
- |
- |
1件: 81 |
17 |
Cortisone |
Cortisone |
D07749 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
18 |
Cortisone acetate |
Cortisone acetate |
D00973 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
19 |
Dectancyl |
- |
- |
- |
- |
1件: 81 |
20 |
Dexamethasone |
Dexamethasone |
D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
21 |
Dexamethasone 0.5mg tablet |
Dexamethasone |
D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
22 |
Dexamethasone 2mg tablets |
Dexamethasone |
D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
23 |
Diurf-006 |
- |
- |
- |
- |
1件: 81 |
24 |
Dual release hydrocortisone (plenadren) |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
25 |
Fludrocortisone |
Fludrocortisone |
D00986, D07967 |
1件: NR3C2 |
1件: Aldosterone-regulated sodium reabsorption |
3件: 6, 17, 81 |
26 |
Flutamide |
Flutamide |
D00586 |
1件: AR |
3件: Oocyte meiosis, Pathways in cancer, Prostate cancer |
1件: 81 |
27 |
Hormonal balance measurements |
Isoxaflutole |
- |
- |
- |
1件: 81 |
28 |
Hydrocortisone |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
29 |
Hydrocortisone (solucortef) |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
30 |
Hydrocortisone 10mg tablet |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
31 |
Hydrocortisone 20mg tablets |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
32 |
Hydrocortisone modified release capsules |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
33 |
Hydrocortisone sodium acetate |
Hydrocortisone, Sodium acetate |
D00088, D01779 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
34 |
Hydrocortisone sodium phosphate |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
3件: 53, 81, 83 |
35 |
Infacort |
- |
- |
- |
- |
1件: 81 |
36 |
Infacort® |
- |
- |
- |
- |
1件: 81 |
37 |
Letrozole |
Letrozole |
D00964 |
1件: CYP19A1 |
3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis |
2件: 81, 89 |
38 |
Metabolic balance measurements |
Isoxaflutole |
- |
- |
- |
1件: 81 |
39 |
Metformin |
Metformin |
D00944, D04966 |
2件: PRKAA1, PRKAA2 |
19件: AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway |
16件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285 |
40 |
Metformin hydrochloride |
Metformin |
D00944, D04966 |
2件: PRKAA1, PRKAA2 |
19件: AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway |
3件: 81, 158, 265 |
41 |
Metformine |
Metformin |
D00944, D04966 |
2件: PRKAA1, PRKAA2 |
19件: AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway |
2件: 81, 299 |
42 |
Metformine sandoz 850 mg filmomhulde tabletten |
Metformin |
D00944, D04966 |
2件: PRKAA1, PRKAA2 |
19件: AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway |
1件: 81 |
43 |
Nbi-74788 |
- |
- |
- |
- |
1件: 81 |
44 |
Nbi-77860 |
- |
- |
- |
- |
1件: 81 |
45 |
Nevanimibe hydrochloride |
- |
- |
- |
- |
1件: 81 |
46 |
Nifedipine |
Nifedipine |
D00437 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
34件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
2件: 50, 81 |
47 |
Phosphate |
Phosphate ion |
- |
- |
- |
29件: 2, 3, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 283, 284, 285, 286, 299 |
48 |
Pioglitazone |
Pioglitazone |
D00945, D08378 |
1件: PPARG |
9件: AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
49 |
Prednisolone |
Prednisolone |
D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
50 |
Prednisolone 1mg tablets |
Prednisolone |
D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
51 |
Prednisolone 5mg tablet |
Prednisolone |
D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |
52 |
Prednisone |
Prednisone |
D00473 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
43件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
53 |
Sodium acetate |
Sodium acetate |
D01779 |
- |
- |
1件: 81 |
54 |
Solu-cortef |
Hydrocortisone succinate |
D01442 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
3件: 6, 81, 83 |
55 |
Spr001 |
- |
- |
- |
- |
1件: 81 |
56 |
Standard care |
- |
- |
- |
- |
2件: 81, 299 |
57 |
Standard glucocorticoid therapy |
- |
- |
- |
- |
1件: 81 |
58 |
Subcutaneous hydrocortisone |
Hydrocortisone |
D00088 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
1件: 81 |