No. |
薬物名(臨床試験情報から抽出) |
DrugBank |
KEGG DRUG * |
KEGG GENES * |
KEGG PATHWAY |
指定難病告示番号 * |
1 |
11c-csar |
- |
- |
- |
- |
2件: 93, 94 |
2 |
3108006977 |
- |
- |
- |
- |
1件: 94 |
3 |
6mp |
Mercaptopurine |
D00161, D04931 |
1件: HPRT1 |
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
2件: 94, 96 |
4 |
Acetylcysteine |
Acetylcysteine |
D00221 |
- |
- |
14件: 6, 13, 19, 20, 49, 51, 58, 85, 94, 111, 164, 233, 298, 299 |
5 |
Acido obeticolico |
- |
- |
- |
- |
1件: 94 |
6 |
All-trans retinoic acid |
Tretinoin |
D00094 |
3件: PML, RARA, RARB |
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
1件: 94 |
7 |
Atra |
Tretinoin |
D00094 |
3件: PML, RARA, RARB |
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
2件: 63, 94 |
8 |
Azathioprine |
Azathioprine |
D00238, D03033 |
- |
- |
18件: 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 65, 66, 85, 94, 95, 96, 97, 162 |
9 |
Bezafibrate |
Bezafibrate |
D01366 |
1件: PPARA |
7件: Adipocytokine signaling pathway, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease (NAFLD), PPAR signaling pathway, cAMP signaling pathway |
5件: 20, 93, 94, 160, 316 |
10 |
Bezalip |
- |
- |
- |
- |
2件: 93, 94 |
11 |
Btt1023 |
- |
- |
- |
- |
1件: 94 |
12 |
Budesonide |
Budesonide |
D00246 |
1件: NR3C1 |
1件: Neuroactive ligand-receptor interaction |
9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 |
13 |
Calcium |
Calcium |
- |
- |
- |
24件: 6, 13, 19, 46, 49, 51, 65, 68, 75, 79, 84, 93, 94, 95, 96, 97, 214, 215, 222, 224, 235, 265, 298, 299 |
14 |
Capecitabine |
Capecitabine |
D01223 |
1件: TYMS |
4件: Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism |
1件: 94 |
15 |
Cenicriviroc |
Cenicriviroc |
D09878 |
2件: CCR2, CCR5 |
9件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral protein interaction with cytokine and cytokine receptor |
1件: 94 |
16 |
Cenicriviroc 150 mg |
Cenicriviroc |
D09878 |
2件: CCR2, CCR5 |
9件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral protein interaction with cytokine and cytokine receptor |
1件: 94 |
17 |
Cilo |
- |
- |
- |
- |
1件: 94 |
18 |
Cilofexor |
Cilofexor |
- |
- |
- |
2件: 93, 94 |
19 |
Cis-4-hydroxy-l-proline |
Proline |
D00035 |
- |
- |
1件: 94 |
20 |
Cladribine |
Cladribine |
D01370 |
1件: RRM1 |
5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
2件: 13, 94 |
21 |
Curcumin |
Curcumin |
- |
- |
- |
10件: 13, 46, 49, 67, 74, 94, 96, 97, 139, 299 |
22 |
Docosahexaenoic acid |
Doconexent |
- |
- |
- |
7件: 6, 49, 90, 94, 240, 299, 301 |
23 |
Docosahexaenoic acid (dha) |
Doconexent |
- |
- |
- |
3件: 6, 94, 299 |
24 |
Dur-928 |
- |
- |
- |
- |
1件: 94 |
25 |
Engineered recombinant human fgf19 |
- |
- |
- |
- |
1件: 94 |
26 |
Erlotinib |
Erlotinib |
D04023, D07907 |
1件: EGFR |
45件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis |
1件: 94 |
27 |
Erlotinib (tarceva) |
Erlotinib |
D04023, D07907 |
1件: EGFR |
45件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis |
1件: 94 |
28 |
Fecal microbiota transplantation |
- |
- |
- |
- |
5件: 2, 66, 94, 96, 97 |
29 |
Fenofibrate |
Fenofibrate |
D00565 |
1件: PPARA |
7件: Adipocytokine signaling pathway, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease (NAFLD), PPAR signaling pathway, cAMP signaling pathway |
5件: 8, 79, 93, 94, 265 |
30 |
Fluimucil*20cpr eff 600mg |
- |
- |
- |
- |
2件: 94, 298 |
31 |
Gluten-free diet |
- |
- |
- |
- |
1件: 94 |
32 |
Htd1801 |
- |
- |
- |
- |
1件: 94 |
33 |
Hymecromone |
Hymecromone |
D00170 |
- |
- |
1件: 94 |
34 |
Int-747, oca |
- |
- |
- |
- |
2件: 93, 94 |
35 |
Lum001 |
- |
- |
- |
- |
3件: 93, 94, 297 |
36 |
Metronidazole |
Metronidazole |
D00409, D05016, D05017 |
- |
- |
8件: 46, 51, 63, 94, 95, 96, 97, 291 |
37 |
Minocycline |
Minocycline |
D00850, D05045 |
- |
- |
13件: 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299 |
38 |
Mitomycin |
Mitomycin |
D00208 |
- |
- |
3件: 94, 162, 329 |
39 |
Mitomycin c |
Mitomycin |
D00208 |
- |
- |
1件: 94 |
40 |
Mizoribine |
Mizoribine |
D01392 |
2件: IMPDH1, IMPDH2 |
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
7件: 49, 51, 53, 66, 94, 222, 224 |
41 |
Ngm282 |
- |
- |
- |
- |
2件: 93, 94 |
42 |
Normal saline |
- |
- |
- |
- |
14件: 6, 17, 22, 36, 46, 49, 60, 94, 96, 211, 226, 276, 296, 299 |
43 |
Norudca |
- |
- |
- |
- |
1件: 94 |
44 |
Norursodeoxycholic acid |
- |
- |
- |
- |
1件: 94 |
45 |
Oca 1,5 mg |
- |
- |
- |
- |
1件: 94 |
46 |
Oca 5 mg |
- |
- |
- |
- |
1件: 94 |
47 |
Oral all-trans retinoic acid (atra) |
Tretinoin |
D00094 |
3件: PML, RARA, RARB |
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
1件: 94 |
48 |
Oral vancomycin |
Vancomycin |
D00212, D00926 |
- |
- |
2件: 94, 296 |
49 |
Orbcel-c |
- |
- |
- |
- |
2件: 94, 95 |
50 |
Phenylbutyrate |
Phenylbutyric acid |
D05868 |
- |
- |
10件: 2, 3, 6, 8, 93, 94, 244, 251, 297, 299 |
51 |
Probiotics |
- |
- |
- |
- |
4件: 94, 96, 97, 291 |
52 |
Proline |
Proline |
D00035 |
- |
- |
2件: 94, 97 |
53 |
Rec-h-fgf19 |
- |
- |
- |
- |
1件: 94 |
54 |
Retinoic acid |
Tretinoin |
D00094 |
3件: PML, RARA, RARB |
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
2件: 94, 231 |
55 |
Rituximab |
Rituximab |
D02994 |
1件: MS4A1 |
1件: Hematopoietic cell lineage |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
56 |
Seladelpar |
- |
- |
- |
- |
2件: 93, 94 |
57 |
Simtuzumab |
Simtuzumab |
- |
- |
- |
2件: 85, 94 |
58 |
Simvastatin |
Simvastatin |
D00434 |
1件: HMGCR |
4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
59 |
Simvastatin 40mg |
Simvastatin |
D00434 |
1件: HMGCR |
4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
1件: 94 |
60 |
Sulfasalazine |
Sulfasalazine |
D00448 |
- |
- |
3件: 46, 94, 271 |
61 |
Thalidomide |
Thalidomide |
D00754 |
1件: TNF |
61件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
62 |
Trans retinoic acid |
Tretinoin |
D00094 |
3件: PML, RARA, RARB |
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
1件: 94 |
63 |
Ucmsc |
- |
- |
- |
- |
1件: 94 |
64 |
Udca |
Ursodeoxycholic acid |
D00734 |
1件: NR1H4 |
1件: Bile secretion |
3件: 93, 94, 97 |
65 |
Ursodeoxycholic acid |
Ursodeoxycholic acid |
D00734 |
1件: NR1H4 |
1件: Bile secretion |
8件: 6, 67, 84, 93, 94, 95, 96, 97 |
66 |
Ursodeoxycholic acid (udca) |
Ursodeoxycholic acid |
D00734 |
1件: NR1H4 |
1件: Bile secretion |
1件: 94 |
67 |
Ursofalk |
Ursodeoxycholic acid |
D00734 |
1件: NR1H4 |
1件: Bile secretion |
4件: 93, 94, 96, 97 |
68 |
Ursolic acid |
- |
- |
- |
- |
1件: 94 |
69 |
Vancomycin |
Vancomycin |
D00212, D00926 |
- |
- |
7件: 46, 70, 94, 96, 97, 296, 299 |
70 |
Vidofludimus |
Vidofludimus |
- |
- |
- |
2件: 94, 97 |
71 |
Vidofludimus calcium |
Vidofludimus |
- |
- |
- |
2件: 94, 97 |
72 |
Xifaxan |
Rifaximin |
D02554 |
- |
- |
2件: 65, 94 |