No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | African trypanosomiasis 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2 | AGE-RAGE signaling pathway in diabetic complications 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3 | Alzheimer disease 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
4 | Amoebiasis 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5 | Antifolate resistance 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
6 | C-type lectin receptor signaling pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
7 | Cellular senescence 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: IL1A |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
8 | Chagas disease (American trypanosomiasis) 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
9 | Cytokine-cytokine receptor interaction 4 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
10 | Cytosolic DNA-sensing pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
11 | Fluid shear stress and atherosclerosis 4 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
12 | Graft-versus-host disease 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
13 | Hematopoietic cell lineage 4 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
14 | Herpes simplex virus 1 infection 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
15 | Human cytomegalovirus infection 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
16 | Human T-cell leukemia virus 1 infection 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
17 | IL-17 signaling pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
18 | Inflammatory bowel disease (IBD) 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
19 | Inflammatory mediator regulation of TRP channels 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
20 | Influenza A 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
21 | Legionellosis 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
22 | Leishmaniasis 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
23 | Malaria 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
24 | MAPK signaling pathway 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
25 | Measles 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
26 | Necroptosis 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
27 | NF-kappa B signaling pathway 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
28 | NOD-like receptor signaling pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
29 | Non-alcoholic fatty liver disease (NAFLD) 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
30 | Osteoclast differentiation 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
31 | Pathogenic Escherichia coli infection 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
32 | Pertussis 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
33 | Prion diseases 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
34 | Prostate cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
35 | Rheumatoid arthritis 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
36 | Salmonella infection 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
37 | Shigellosis 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
38 | Th17 cell differentiation 2 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
39 | TNF signaling pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
40 | Toll-like receptor signaling pathway 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
41 | Transcriptional misregulation in cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
42 | Tuberculosis 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
43 | Type I diabetes mellitus 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
44 | Yersinia infection 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |