No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adherens junction 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
2 | Adrenergic signaling in cardiomyocytes 5 genes, 1 drug (DrugBank) and 5 diseases shown |
5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
3 | Alcoholism 6 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
4 | Aldosterone synthesis and secretion 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
6 | Allograft rejection 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
7 | Alzheimer disease 9 genes, 3 drugs (DrugBank) and 15 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
8 | Amphetamine addiction 11 genes, 3 drugs (DrugBank) and 15 diseases shown |
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
9 | AMPK signaling pathway 2 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
10 | Amyotrophic lateral sclerosis (ALS) 7 genes, 3 drugs (DrugBank) and 15 diseases shown |
2件: GRIA1, GRIA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
11 | Antigen processing and presentation 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
12 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
13 | Asthma 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
14 | Autoimmune thyroid disease 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
15 | Bile secretion 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: CA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
16 | Calcium signaling pathway 9 genes, 4 drugs (DrugBank) and 18 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
17 | cAMP signaling pathway 14 genes, 4 drugs (DrugBank) and 18 diseases shown |
8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
18 | Carbohydrate digestion and absorption 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: CACNA1D |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
19 | Cardiac muscle contraction 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
20 | Cell adhesion molecules (CAMs) 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
21 | Cellular senescence 7 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: CACNA1D |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
22 | cGMP-PKG signaling pathway 5 genes, 2 drugs (DrugBank) and 6 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
23 | Cholinergic synapse 5 genes, 2 drugs (DrugBank) and 12 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
24 | Circadian entrainment 11 genes, 3 drugs (DrugBank) and 15 diseases shown |
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
25 | Cocaine addiction 7 genes, 4 drugs (DrugBank) and 18 diseases shown |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
1件: GRIA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
26 | Collecting duct acid secretion 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: CA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
27 | Cortisol synthesis and secretion 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
28 | Cushing syndrome 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
29 | Dilated cardiomyopathy (DCM) 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
30 | Dopaminergic synapse 10 genes, 4 drugs (DrugBank) and 18 diseases shown |
7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
31 | Endocytosis 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
32 | Epstein-Barr virus infection 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
33 | FoxO signaling pathway 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: S1PR1 |
D10001 |
Fingolimod |
4件: 2, 13, 14, 156 |
34 | GABAergic synapse 20 genes, 1 drug (DrugBank) and 5 diseases shown |
20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
35 | Gap junction 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: DRD2, HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
36 | Gastric acid secretion 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: CA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
37 | Glutamatergic synapse 16 genes, 3 drugs (DrugBank) and 15 diseases shown |
11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
38 | Glycerophospholipid metabolism 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
39 | GnRH secretion 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
40 | GnRH signaling pathway 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
41 | Graft-versus-host disease 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
42 | Growth hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
43 | Hematopoietic cell lineage 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
44 | Herpes simplex virus 1 infection 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
45 | HIF-1 signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
46 | Human cytomegalovirus infection 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
47 | Human immunodeficiency virus 1 infection 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
48 | Human papillomavirus infection 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
49 | Human T-cell leukemia virus 1 infection 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
50 | Huntington disease 2 genes, 2 drugs (DrugBank) and 12 diseases shown |
2件: GRIN1, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
51 | Hypertrophic cardiomyopathy (HCM) 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
52 | Inflammatory bowel disease (IBD) 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
53 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
54 | Influenza A 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
55 | Insulin resistance 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
56 | Insulin secretion 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
57 | Insulin signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
58 | Intestinal immune network for IgA production 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
59 | Kaposi sarcoma-associated herpesvirus infection 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
60 | Leishmaniasis 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
61 | Long-term depression 3 genes, 1 drug (DrugBank) and 5 diseases shown |
3件: GRIA1, GRIA2, GRIA3 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
62 | Long-term potentiation 8 genes, 3 drugs (DrugBank) and 15 diseases shown |
3件: CACNA1C, GRIA1, GRIA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
63 | Longevity regulating pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
64 | Longevity regulating pathway - multiple species 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
65 | MAPK signaling pathway 5 genes, 2 drugs (DrugBank) and 6 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
66 | Metabolic pathways 3 genes, 2 drugs (DrugBank) and 13 diseases shown |
2件: CA2, CA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
67 | Morphine addiction 16 genes, 1 drug (DrugBank) and 5 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
68 | mTOR signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
69 | Natural killer cell mediated cytotoxicity 5 genes, 1 drug (DrugBank) and 4 diseases shown |
5件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
70 | Neuroactive ligand-receptor interaction 33 genes, 5 drugs (DrugBank) and 19 diseases shown |
2件: DRD2, HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
1件: S1PR1 |
D10001 |
Fingolimod |
4件: 2, 13, 14, 156 |
71 | Nicotine addiction 25 genes, 3 drugs (DrugBank) and 15 diseases shown |
20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
72 | Nitrogen metabolism 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: CA2, CA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
73 | Non-alcoholic fatty liver disease (NAFLD) 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
74 | Ovarian steroidogenesis 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
75 | Oxytocin signaling pathway 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
76 | Pancreatic secretion 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: CA2 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
77 | Parkinson disease 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
78 | Phagosome 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
79 | Phospholipase D signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
80 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
81 | Proximal tubule bicarbonate reclamation 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: CA2, CA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
82 | Rap1 signaling pathway 5 genes, 4 drugs (DrugBank) and 15 diseases shown |
1件: DRD2 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
83 | Ras signaling pathway 4 genes, 3 drugs (DrugBank) and 12 diseases shown |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
84 | Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
85 | Renin secretion 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
86 | Retrograde endocannabinoid signaling 24 genes, 1 drug (DrugBank) and 5 diseases shown |
24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
87 | Rheumatoid arthritis 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
88 | Serotonergic synapse 9 genes, 3 drugs (DrugBank) and 10 diseases shown |
7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
1件: SLC6A4 |
D00812 |
Desipramine |
2件: 120, 156 |
D07791 |
89 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: S1PR1 |
D10001 |
Fingolimod |
4件: 2, 13, 14, 156 |
90 | Staphylococcus aureus infection 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
91 | Synaptic vesicle cycle 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: SLC6A2, SLC6A4 |
D00812 |
Desipramine |
2件: 120, 156 |
D07791 |
92 | Systemic lupus erythematosus 16 genes, 3 drugs (DrugBank) and 12 diseases shown |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
93 | Taste transduction 10 genes, 1 drug (DrugBank) and 5 diseases shown |
10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
94 | Terpenoid backbone biosynthesis 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
95 | Th1 and Th2 cell differentiation 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
96 | Th17 cell differentiation 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
97 | Tight junction 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: CACNA1D |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
98 | Toxoplasmosis 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
99 | Transcriptional misregulation in cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: GRIA3 |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
100 | Tuberculosis 14 genes, 1 drug (DrugBank) and 4 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
101 | Type I diabetes mellitus 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
102 | Type II diabetes mellitus 3 genes, 2 drugs (DrugBank) and 6 diseases shown |
2件: CACNA1C, CACNA1D |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
103 | Vascular smooth muscle contraction 4 genes, 1 drug (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00537 |
Topiramate |
5件: 6, 140, 144, 156, 193 |
104 | Viral carcinogenesis 6 genes, 1 drug (DrugBank) and 4 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
105 | Viral myocarditis 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |