No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adrenergic signaling in cardiomyocytes 2 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2 | AGE-RAGE signaling pathway in diabetic complications 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
3 | Alcoholism 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
4 | Aldosterone synthesis and secretion 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
5 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: NR3C2 |
D01115 |
Eplerenone |
3件: 75, 113, 215 |
6 | Alzheimer disease 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
7 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
8 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
9 | Apelin signaling pathway 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
10 | Calcium signaling pathway 6 genes, 3 drugs (DrugBank) and 22 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
11 | cAMP signaling pathway 6 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
12 | cGMP-PKG signaling pathway 5 genes, 3 drugs (DrugBank) and 28 diseases shown |
3件: ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
13 | Circadian entrainment 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
14 | Cocaine addiction 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
15 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
16 | Cortisol synthesis and secretion 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
17 | Cushing syndrome 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
18 | Dilated cardiomyopathy (DCM) 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
19 | Dopaminergic synapse 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: GRIN2A, GRIN2B |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
20 | Estrogen signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
21 | Gap junction 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
22 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
23 | Huntington disease 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: GRIN1, GRIN2B |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
24 | Influenza A 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
25 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
26 | Morphine addiction 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
27 | Neuroactive ligand-receptor interaction 12 genes, 6 drugs (DrugBank) and 32 diseases shown |
3件: ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
28 | Nicotine addiction 5 genes, 1 drug (DrugBank) and 6 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
29 | Pathways in cancer 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
30 | Phospholipase D signaling pathway 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
31 | Rap1 signaling pathway 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GRIN1, GRIN2A, GRIN2B |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
32 | Ras signaling pathway 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GRIN1, GRIN2A, GRIN2B |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
33 | Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
34 | Renin secretion 2 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
35 | Renin-angiotensin system 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
36 | Salivary secretion 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
37 | Staphylococcus aureus infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
38 | Systemic lupus erythematosus 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: GRIN2A, GRIN2B |
D00711 |
Ketamine |
6件: 6, 13, 70, 113, 156, 215 |
D08098 |
39 | Vascular smooth muscle contraction 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |