Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z other
No. | KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * | KEGG DRUG * | DrugBank | 指定難病告示番号 * |
1 | Alcoholism |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
2件: DRD1, DRD2 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 | ||
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
2 | Alzheimer disease |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
3 | Amphetamine addiction |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
1件: DRD1 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 | ||
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
4 | Amyotrophic lateral sclerosis (ALS) |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
5 | Calcium signaling pathway |
2件: DRD1, DRD5 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
6 | cAMP signaling pathway |
3件: DRD1, DRD2, DRD5 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
7 | cGMP-PKG signaling pathway |
3件: ADRA2A, ADRA2B, ADRA2C | D00514 | Dexmedetomidine | 11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 | |||||
8 | Circadian entrainment |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
9 | Cocaine addiction |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
2件: DRD1, DRD2 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 | ||
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
10 | Cortisol synthesis and secretion |
1件: KCNA4 | D04127 | Dalfampridine | 3件: 3, 4, 13 |
11 | Cushing syndrome |
1件: KCNA4 | D04127 | Dalfampridine | 3件: 3, 4, 13 |
12 | Dopaminergic synapse |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
5件: DRD1, DRD2, DRD3, DRD4, DRD5 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 | ||
2件: GRIN2A, GRIN2B | D07283 | Esketamine | 3件: 2, 4, 70 | ||
13 | ECM-receptor interaction |
1件: SV2A | D00709 | Levetiracetam | 4件: 2, 4, 6, 13 |
14 | Gap junction |
2件: DRD1, DRD2 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
15 | Glutamatergic synapse |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
16 | Huntington disease |
2件: GRIN1, GRIN2B | D07283 | Esketamine | 3件: 2, 4, 70 |
17 | Long-term potentiation |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
18 | Metabolic pathways |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
19 | Morphine addiction |
1件: DRD1 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
20 | Neuroactive ligand-receptor interaction |
3件: ADRA2A, ADRA2B, ADRA2C | D00514 | Dexmedetomidine | 11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 | |||||
5件: DRD1, DRD2, DRD3, DRD4, DRD5 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 | ||
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 | ||
21 | Nicotine addiction |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D | D07283 | Esketamine | 3件: 2, 4, 70 |
22 | Parkinson disease |
2件: DRD1, DRD2 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
23 | Phenylalanine metabolism |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
24 | Rap1 signaling pathway |
1件: DRD2 | D00059 | Levodopa | 7件: 2, 4, 6, 17, 90, 164, 201 |
3件: GRIN1, GRIN2A, GRIN2B | D07283 | Esketamine | 3件: 2, 4, 70 | ||
25 | Ras signaling pathway |
3件: GRIN1, GRIN2A, GRIN2B | D07283 | Esketamine | 3件: 2, 4, 70 |
26 | Serotonergic synapse |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
1件: KCND2 | D04127 | Dalfampridine | 3件: 3, 4, 13 | ||
27 | Systemic lupus erythematosus |
2件: GRIN2A, GRIN2B | D07283 | Esketamine | 3件: 2, 4, 70 |
28 | Tryptophan metabolism |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |
29 | Tyrosine metabolism |
1件: DDC | D00558 | Carbidopa | 8件: 2, 4, 6, 13, 17, 90, 164, 201 |